Proceedings Paper
In-vivo photodynamic therapy dosimeter| Format | Member Price | Non-Member Price |
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Paper Abstract
A fiberoptic isotropic probe system has been developed to
measure both the Space Irradiance (SI) and Fluorescence (F)
within tissue during Photodynamic Therapy (PDT). The probe
is 0.8mm in diameter. The system has a SI sensitivity of
0.1 mW/cm2 and a F sensitivity of 0.1 microgram per
milliliter of DHE in a tissue phantom solution. It also
provides for the time integrated SI and F and a ratio of the
F to SI. A biological response study is being undertaken
using DHE to determine the correlation of therapeutic
response with drug dose, light dose, integrated space
irradiance, and integrated fluorescence in a standardized
animal tumor model. Description of the device and its
performance will be presented along with preliminary results
of animal tumor model studies.
Paper Details
Date Published: 1 July 1990
PDF: 11 pages
Proc. SPIE 1203, Photodynamic Therapy: Mechanisms II, (1 July 1990);
Published in SPIE Proceedings Vol. 1203:
Photodynamic Therapy: Mechanisms II
Thomas J. Dougherty, Editor(s)
PDF: 11 pages
Proc. SPIE 1203, Photodynamic Therapy: Mechanisms II, (1 July 1990);
Show Author Affiliations
J. Brian Dunn, LaserTherapeutics, Inc. (United States)
P. Cusimano, LaserTherapeutics, Inc. (United States)
Daniel R. Doiron, LaserTherapeutics, Inc. (United States)
P. Cusimano, LaserTherapeutics, Inc. (United States)
Daniel R. Doiron, LaserTherapeutics, Inc. (United States)
Charles J. Gomer, Childrens Hospital of Los Angeles and Univ. of Southern California School of Medicine (United States)
A. Edward Profio, Univ. of California/Santa Barbara (United States)
A. Edward Profio, Univ. of California/Santa Barbara (United States)
Published in SPIE Proceedings Vol. 1203:
Photodynamic Therapy: Mechanisms II
Thomas J. Dougherty, Editor(s)
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