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Proceedings Paper

Intraluminal ultrasound guidance of transverse laser coronary atherectomy
Author(s): H. Thomas Aretz M.D.; Michael A. Martinelli; Earl G. LeDet; Tomas Sedlacek; G. Frederick Hatch; Richard E. Gregg
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Paper Abstract

A coronary laser atherectomy system combining laser delivery and ultrasonic imaging capability is described. The system is being developed by Intra-Sonix, Inc. to treat severe stenoses. The imaging system provides the clinician with the guidance needed to remove substantial plaque without perforation. The ultrasound transducers and laser optics are mounted in a small (less than 4 F), flexible catheter, that is deliverable over a standard guidewire (0.016 inch). The laser and ultrasound beams are directed at the artery wall to permit debulking of lesions and ultrasonic depth profiling of the tissue structure throughout the thickness of the artery. This allows the physician to determine the level of therapy to be applied and to monitor the plaque removal as the therapy progresses. The precise location of the ultrasound and laser beams in the artery is determined by a navigation system. Navigation data are processed electronically in conjunction with ultrasound data to produce real-time cross-sectional and longitudinal images of the artery wall at selected locations, which are updated as the catheter progresses through the vessel lumen. Results of in vitro tests on human atherosclerotic arteries and early in vivo experiments in a canine-human xenograft model showing image construction and radial laser delivery are discussed.

Paper Details

Date Published: 1 July 1990
PDF: 11 pages
Proc. SPIE 1201, Optical Fibers in Medicine V, (1 July 1990); doi: 10.1117/12.17520
Show Author Affiliations
H. Thomas Aretz M.D., Lahey Clinic Medical Ctr. (United States)
Michael A. Martinelli, Intra-Sonix, Inc. (United States)
Earl G. LeDet, Intra-Sonix, Inc. (United States)
Tomas Sedlacek, Intra-Sonix, Inc. (United States)
G. Frederick Hatch, Intra-Sonix, Inc. (United States)
Richard E. Gregg, Intra-Sonix, Inc. (United States)

Published in SPIE Proceedings Vol. 1201:
Optical Fibers in Medicine V
Abraham Katzir, Editor(s)

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