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Proceedings Paper

Automatic technique for localizing externally attached markers in MR and CT volume images of the head
Author(s): Matthew Yang Wang; J. Michael Fitzpatrick; Calvin R. Maurer Jr.; Robert J. Maciunas
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Paper Abstract

An image processing technique is presented here for finding centroids of cylindrical fiducial markers attached externally to the human head in CT and MR volume images. The centroids can be used for image registration. The technique, which is fast, automatic, and knowledge-based, has two major steps. First, it searches the whole image volume to find all markerlike objects and gets a position inside each object. We call this position a 'seed' point, and we call the object a candidate marker. Second, it selects the voxels surrounding the seed voxel as marker or non-marker voxels using knowledge-based rules and provides an intensity weighted centroid for each true marker. We call this final centroid the 'fiducial' point of the marker. The technique has been developed on forty-two scans of six patients -- one CT and six MR scans per patient. There were four markers attached to each patient for a total of 168 marker images. On these images the technique exhibits no false positives or false negatives for CT. For MR the false positive rate and the false negative rate are both 1.4%. To evaluate the accuracy of the fiducial points MR-CT registration was performed using geometrical correction for the MR images. The fiducial registration accuracies averaged 0.4 mm and were better that 0.6 mm on each of the eighteen image pairs.

Paper Details

Date Published: 11 May 1994
PDF: 11 pages
Proc. SPIE 2167, Medical Imaging 1994: Image Processing, (11 May 1994); doi: 10.1117/12.175056
Show Author Affiliations
Matthew Yang Wang, Vanderbilt Univ. (United States)
J. Michael Fitzpatrick, Vanderbilt Univ. (United States)
Calvin R. Maurer Jr., Vanderbilt Univ. (United States)
Robert J. Maciunas, Vanderbilt Univ. (United States)

Published in SPIE Proceedings Vol. 2167:
Medical Imaging 1994: Image Processing
Murray H. Loew, Editor(s)

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