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Proceedings Paper

Photodynamic effects on T-cells and skin lesions of a patient with mycosis fungoides using porphyrin photosensitizers
Author(s): Karsten Koenig; Wolf-Henning Boehncke; Angelika C. Rueck; Roland Kaufmann; Rudolf W. Steiner; Wolfram Sterry
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Paper Abstract

PUVA is a well established phototreatment modality for various dermatoses, like T cell lymphomas, using long-wavelength UV radiation. In contrast, PDT bases on the combination of photosensitizers, especially porphyrins, and radiation mainly in the red spectral region. We analyzed the photochemical effects of both treatments on cell lines MyLa and HuT78, established from patients with cutaneous T cell lymphomas. Our observations document the capability of PDT to inhibit proliferation of transformed T cells similar to PUVA thus pointing out its potential in the treatment of cutaneous T cell lymphomas.

Paper Details

Date Published: 15 February 1994
PDF: 9 pages
Proc. SPIE 2086, Medical Applications of Lasers, (15 February 1994); doi: 10.1117/12.169144
Show Author Affiliations
Karsten Koenig, Institute for Lasertechnology in Medicine (Germany)
Wolf-Henning Boehncke, Univ. Ulm (Germany)
Angelika C. Rueck, Institute for Lasertechnology in Medicine (Germany)
Roland Kaufmann, Univ. Ulm (Germany)
Rudolf W. Steiner, Institute for Lasertechnology in Medicine (Germany)
Wolfram Sterry, Univ. Ulm (Germany)

Published in SPIE Proceedings Vol. 2086:
Medical Applications of Lasers
Kazuhiko Atsumi M.D.; Cornelius Borst M.D.; Frank W. Cross M.D.; Herbert J. Geschwind M.D.; Dieter Jocham; Jan Kvasnicka; Hans H. Scherer M.D.; Mario A. Trelles; Eberhard Unsoeld, Editor(s)

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