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Proceedings Paper

Tissue optics and dosimetry for photodynamic cancer therapy in the esophagus
Author(s): Roland Bays; Georges A. Wagnieres; Daniel Braichotte; Hubert van den Bergh; Philippe Monnier; Jean-Francois Savary
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Paper Abstract

For safe light dosimetry in photodynamic therapy (PDT) in organs like the oesophagus, the knowledge of the space irradiance distribution in tissue is especially important. In order to obtain this distribution we are studying two methods which are being evaluated in a clinical environment. The first method is non invasive and is based on the measurement of optical tissue parameters. For this measurement, several types of optical probe have been developed. The second method is invasive and measures light in situ by means of an optical fiber probe with a fluorescent tip. Together with these measuring techniques and results we present some simple notions of light dosimetry which can be used to improve the safety and the efficacy of the clinical PDT.

Paper Details

Date Published: 1 March 1994
PDF: 14 pages
Proc. SPIE 2078, Photodynamic Therapy of Cancer, (1 March 1994); doi: 10.1117/12.168710
Show Author Affiliations
Roland Bays, Ecole Polytechnique Federale de Lausanne (Switzerland)
Georges A. Wagnieres, Ecole Polytechnique Federale de Lausanne (Switzerland)
Daniel Braichotte, Ecole Polytechnique Federale de Lausanne (Switzerland)
Hubert van den Bergh, Ecole Polytechnique Federale de Lausanne (Switzerland)
Philippe Monnier, CHUV Hospital (Switzerland)
Jean-Francois Savary, CHUV Hospital (Switzerland)

Published in SPIE Proceedings Vol. 2078:
Photodynamic Therapy of Cancer
Giulio Jori; Johan Moan; Willem M. Star, Editor(s)

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