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Proceedings Paper

1.5-um resolution optical low-coherence reflectometry in biological tissues
Author(s): Xavier Clivaz; Fabienne D. Marquis-Weible; Rene-Paul Salathe
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Paper Abstract

An Optical Low Coherence Reflectometer with a spatial resolution of 1.5 micrometers (FWHM) in biological tissue has been developed. This high resolution is obtained using the fluorescence generated by an Ar-laser pumped Ti-Sapphire crystal. Measurements have been performed on freshly excised pig eyes and bovine mesenteric arterial walls, as examples of transparent and diffusive biological tissues, respectively. The improved spatial resolution is used to determine more precisely optical distances and to resolve details of the intima structure.

Paper Details

Date Published: 1 February 1994
PDF: 9 pages
Proc. SPIE 2083, Microscopy, Holography, and Interferometry in Biomedicine, (1 February 1994); doi: 10.1117/12.167408
Show Author Affiliations
Xavier Clivaz, Swiss Federal Institute of Technology (Switzerland)
Fabienne D. Marquis-Weible, Swiss Federal Institute of Technology (Switzerland)
Rene-Paul Salathe, Swiss Federal Institute of Technology (Switzerland)

Published in SPIE Proceedings Vol. 2083:
Microscopy, Holography, and Interferometry in Biomedicine
Adolf Friedrich Fercher; Aaron Lewis; Halina Podbielska M.D.; Herbert Schneckenburger; Tony Wilson, Editor(s)

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