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Proceedings Paper

Fluorescence diagnostic of wound processes
Author(s): Nikita Yu. Konstantinov; Mikhail M. Terent'ev; Igor V. Rybakovskii
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Paper Abstract

A set for fluorescence detection of laser-induced processes in biological tissues in the spectral range from 200 nm to 1000 nm was applied for fluorescence diagnostics of wound processes. The water-soluble photosensitizer and tumor-making agent--sulphonated aluminum phthalocyanine (AlPcS) were tested for vital decoration of wound processes. The spectral (optical multichannel analyzer) and image (slow-scan CCD camera) detection of wound process were performed. A high efficiency of laser-induced dye-related fluorescence for wound processes detection and monitoring was demonstrated. The distribution of dye between untreated tissues and different wounds, inflammations and experimental tumors is described. The extremely long uptake time (up to 8 weeks) for AlPcS in wounds and inflammations was observed.

Paper Details

Date Published: 15 January 1994
PDF: 8 pages
Proc. SPIE 2081, Optical Biopsy, (15 January 1994); doi: 10.1117/12.166814
Show Author Affiliations
Nikita Yu. Konstantinov, Institute of Physical Chemistry (Russia)
Mikhail M. Terent'ev, Institute of Physical Chemistry (Russia)
Igor V. Rybakovskii, Institute of Physical Chemistry (Russia)

Published in SPIE Proceedings Vol. 2081:
Optical Biopsy
Rinaldo Cubeddu; Sune Svanberg; Hubert van den Bergh, Editor(s)

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