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Proceedings Paper

Fourier transform infrared spectroscopic studies on DNA polymorphism
Author(s): W. P. Pohle; Hartmut Fritzsche
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Paper Abstract

DNA as a biopolymeric molecule standing directly in the center of the molecular biological processing in the cell exhibits a pronounced polymorphism. Infrared spectroscopy (IRS) is a very suitable tool to perform conformational analyses of DNA especially when using its Fourier transform (FT) version and/or the linear dichroism (LD). Spectral features of the sugar-phosphate backbone and of the bases of DNA can be utilized to characterize aspects of DNA conformation as illustrated for the A and B forms and for the unusual parallel-stranded (ps) form of DNA, respectively.

Paper Details

Date Published: 31 January 1994
PDF: 2 pages
Proc. SPIE 2089, 9th International Conference on Fourier Transform Spectroscopy, (31 January 1994); doi: 10.1117/12.166674
Show Author Affiliations
W. P. Pohle, Friedrich-Schiller Univ. Jena (Germany)
Hartmut Fritzsche, Friedrich-Schiller Univ. Jena (Germany)


Published in SPIE Proceedings Vol. 2089:
9th International Conference on Fourier Transform Spectroscopy
John E. Bertie; Hal Wieser, Editor(s)

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