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Proceedings Paper

Fourier transform infrared studies on conformational changes of calmodulin induced by metal-ion binding
Author(s): Masayuki Nara; Masaru Tanokura; Mitsuo Tasumi
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Paper Abstract

Fourier transform infrared (FT-IR) spectroscopy has been used to examine conformational changes of calmodulin (CaM) by metal-ion binding. It has been found that the amide-I mode and the COO- stretching modes are markers for investigating the effects of metal- ion binding on CaM. These modes indicate that the effect of Mg2+ on CaM is different from that of Ca2+, and that the effects of Sr2+ and Cd2+ on CaM are similar to but not identical with that of Ca2+. This result suggests that the metal -COO- interaction is one of the important factors regulating the 3-D structure of CaM.

Paper Details

Date Published: 31 January 1994
PDF: 2 pages
Proc. SPIE 2089, 9th International Conference on Fourier Transform Spectroscopy, (31 January 1994); doi: 10.1117/12.166602
Show Author Affiliations
Masayuki Nara, Univ. of Tokyo (Japan)
Masaru Tanokura, Univ. of Tokyo (Japan)
Mitsuo Tasumi, Univ. of Tokyo (Japan)

Published in SPIE Proceedings Vol. 2089:
9th International Conference on Fourier Transform Spectroscopy
John E. Bertie; Hal Wieser, Editor(s)

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