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Proceedings Paper

Imaging of biological tissues by means of a time-gated confocal scanning: experimental and numerical results
Author(s): Giovanni Zaccanti; Piero Bruscaglioni; F. Martinelli; Massimo Gurioli; Renzo Salimbeni; Marco Ferrari
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Paper Abstract

Numerical and experimental results of a study carried out to investigate the capabilities of the time gating technique to enhance images of biological tissues are reported. In particular we have investigated the confocal scanning configuration. The experimental results were obtained by using a picosecond laser and a streak camera system. The numerical results were obtained by using Monte Carlo simulations. Both elementary and semianalytic Monte Carlo methods were used. The numerical results showed that by using the time gating technique the contrast can be significantly increased when a short gating time is used. The measured time resolved spread functions were in general good agreement with numerical results. However, the experimental results showed that with our experimental setup it is difficult to measure with sufficient accuracy the small energy received during a short gating time when the slab of tissue is larger than 1 cm.

Paper Details

Date Published: 14 September 1993
PDF: 7 pages
Proc. SPIE 1888, Photon Migration and Imaging in Random Media and Tissues, (14 September 1993); doi: 10.1117/12.154675
Show Author Affiliations
Giovanni Zaccanti, Univ. of Florence (Italy)
Piero Bruscaglioni, Univ. of Florence (Italy)
F. Martinelli, Univ. of Florence (Italy)
Massimo Gurioli, LENS Lab. (Italy)
Renzo Salimbeni, Istituto di Elettronica Quantistica/CNR (Italy)
Marco Ferrari, Univ. of L'Aquila (Italy)

Published in SPIE Proceedings Vol. 1888:
Photon Migration and Imaging in Random Media and Tissues
Britton Chance; Robert R. Alfano, Editor(s)

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