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Proceedings Paper

Laser-fluorescent pulses as a probe to brain energy and efficiency
Author(s): Zheng Shen; Shuzhi Lin
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Paper Abstract

A specific electrode was made of quartz optic fibers with a thin metal membrane, the quartz core guided nitrogen laser beam (10 - 40 (mu) j/pulse, I pulse/sec.) into brain cortex, and got out fluorescent pulses emitted by brain NADH and FAD moleculars. The amplitudes of laser- fluorescent pulses represented brain NADH and FAD concentrations determined by HPLC methods. The metal membrane outside optic fiber (1*10 micrometers 2, 40 mm long) as a specific electrode recorded neural discharges. The neural pulses represented neuron activities. The ratio of frequency changes of neural discharges to the amplitude changes of laser- fluorescent pulses was written as (eta) equals dFi/dAi, which (eta) means neuron efficiency. The results showed that intensity of nitrogen beam increased the amplitudes of laser-fluorescent pulses and decreased the (eta) value. Electric stimuli increased the frequency of neural discharges and increased the (eta) value. The results mean that low power laser beam guided into brain by optic fibers can work as a stimulant factor as well as a probe to brain function.

Paper Details

Date Published: 14 July 1993
PDF: 7 pages
Proc. SPIE 1883, Low-Energy Laser Effects on Biological Systems, (14 July 1993); doi: 10.1117/12.148012
Show Author Affiliations
Zheng Shen, Peking Univ. (China)
Shuzhi Lin, Peking Univ. (China)

Published in SPIE Proceedings Vol. 1883:
Low-Energy Laser Effects on Biological Systems
Michal Schwartz; Michael Belkin M.D., Editor(s)

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