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Proceedings Paper

Analysis of erythrocyte flexibility by means of laser diffraction: rigidification due to defined shearing
Author(s): Rainer Bayer; Guido Wolf
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Paper Abstract

A newly developed system to determine red blood cell flexibility is presented. It combines ektacytometry (laser diffraction) with image analysis. Laser light is passed through erythrocyte suspensions which are sheared in a Cuette like viscosimeter. The laser diffraction patterns are photographed by a CCD camera, and further analyzed by a computer. Flexibility is characterized by the quotient of minor and major axes of isointensity lines of the elliptically transformed diffraction patterns. The variation coefficient of the measurement is less than 1%.

Paper Details

Date Published: 2 June 1993
PDF: 12 pages
Proc. SPIE 1981, Optical Methods of Biomedical Diagnostics and Therapy, (2 June 1993); doi: 10.1117/12.146478
Show Author Affiliations
Rainer Bayer, Univ. Duesseldorf (Germany)
Guido Wolf, Univ. Duesseldorf (Germany)

Published in SPIE Proceedings Vol. 1981:
Optical Methods of Biomedical Diagnostics and Therapy
Valery V. Tuchin, Editor(s)

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