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Proceedings Paper

Diagnostic potentials of laser nephelometry of aggregating erythrocytes suspension
Author(s): Nikolai N. Firsov; Alexander V. Priezzhev; Olga M. Ryaboshapka; Igor V. Sirko
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Paper Abstract

The viscous properties of blood are of major importance for circulation in vessels with diameters less than 100 mm. The disturbance of microcirculation is observed in many pathologies. The blood viscosity under low shear rates is determined by the aggregation ability of erythrocytes. So, an important problem of hemorheology is the determination of the durability of aggregates, their sizes, and the aggregation kinetics. To measure these parameters the nephelometric technique is widely applied in different modifications enabling the registration of the backscattered or the transmitted light intensity. We present here the results of our study of peculiarities of the (dis)aggregation kinetics in relation to different pathologies: psoriatic arthritis, inherited hypercholesteremia, inherited homoglobinopathy, and some others. These results show the high diagnostic potentials of laser nephelometric technique.

Paper Details

Date Published: 17 June 1993
PDF: 6 pages
Proc. SPIE 1922, Laser Study of Macroscopic Biosystems, (17 June 1993);
Show Author Affiliations
Nikolai N. Firsov, Russian State Medical Univ. (Russia)
Alexander V. Priezzhev, Moscow State Univ. (Russia)
Olga M. Ryaboshapka, Moscow State Univ. (Russia)
Igor V. Sirko, Russian State Medical Univ. (Russia)

Published in SPIE Proceedings Vol. 1922:
Laser Study of Macroscopic Biosystems
Jouko E. Korppi-Tommola, Editor(s)

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