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Proceedings Paper

Fiber optic spectroscopy of blood for oxygen saturation sensor development: hematocrit effect
Author(s): Charles D. Anderson; Marek T. Wlodarczyk
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Paper Abstract

We present experimental results from fiberoptic spectroscopy apparatus measuring whole blood's optical attenuation over a continuous wavelength range of 0.6 - 1.0 micrometers . Relative optical density (OD) spectra at a number of hematocrit values and oxygenation levels is obtained. The role of hematocrit in affecting spectral shape is discussed based upon relatively simple relationships derived from experimental data. A specific partial differential equation emerges from the analysis. This equation relates scatter-dependent experimental OD to oxygen saturation, hematocrit and purely absorbing, nonscattering constituents--and is obeyed over an extended wavelength range. A three-wavelength algorithm using experimental absorbances at LED-compatible wavelengths accurately provides both hematocrit and oxygen saturation values, for hematocrit levels between 0.2 and 0.6 in the presence of oxygenated and reduced Hb species. Optical system comparison between spectroscopic data and modeled LED behavior indicates the algorithm can be mapped to the design and implementation of discrete components for clinical use.

Paper Details

Date Published: 21 May 1993
PDF: 10 pages
Proc. SPIE 1886, Fiber Optic Sensors in Medical Diagnostics, (21 May 1993); doi: 10.1117/12.144840
Show Author Affiliations
Charles D. Anderson, FiberOptic Sensor Technologies, Inc. (United States)
Marek T. Wlodarczyk, FiberOptic Sensor Technologies, Inc. (United States)

Published in SPIE Proceedings Vol. 1886:
Fiber Optic Sensors in Medical Diagnostics
Fred P. Milanovich, Editor(s)

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