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Proceedings Paper

MR-guided laser interventions
Author(s): Martin Bettag; Frank Ulrich; Wolfgang J. Bock; Thomas Kahn M.D.; Hans-Joachim Schwarzmaier M.D.; Stefan Frank F. Hessel
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Paper Abstract

Low-power interstitial thermal therapy using a 1064 nm Nd:YAG laser and a newly designed fiberoptic transmission system, the ITT laser fiber, is a promising therapeutic approach in the treatment of cerebral tumors. After CT-guided stereotactic implantation of an applicator probe, we performed laser-induced interstitial thermal therapy in a patient with an astrocytomas WHO grade II under simultaneous magnetic resonance imaging (MRI) control. In order to assess the effects of the treatment a 2D-Flash sequence with an acquisition time of 15 sec was used. It could be demonstrated that laser-tissue interactions progressed with duration of irradiation depending on laser powers applied. There was a well-defined area of tissue necrosis with a maximum size of 17 mm in diameter in the center of the tumor and a small zone of transient perifocal edema. With regard to experimental studies, it seems to be possible to define between reversible and irreversible laser-tissue effects.

Paper Details

Date Published: 1 June 1992
PDF: 7 pages
Proc. SPIE 1643, Laser Surgery: Advanced Characterization, Therapeutics, and Systems III, (1 June 1992); doi: 10.1117/12.137331
Show Author Affiliations
Martin Bettag, Heinrich-Heine Univ. Medical School (Germany)
Frank Ulrich, Heinrich-Heine Univ. Medical School (Germany)
Wolfgang J. Bock, Heinrich-Heine Univ. Medical School (Germany)
Thomas Kahn M.D., Heinrich-Heine Univ. Medical School (Germany)
Hans-Joachim Schwarzmaier M.D., Heinrich-Heine Univ. Medical School (Germany)
Stefan Frank F. Hessel, MBB-Medizintechnik GmbH (Germany)

Published in SPIE Proceedings Vol. 1643:
Laser Surgery: Advanced Characterization, Therapeutics, and Systems III
R. Rox Anderson M.D., Editor(s)

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