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Proceedings Paper

Preventive effect of antihistaminics on mouse skin photosensitization with hematoporphyrin derivative
Author(s): Nai-wu Fu; Li-xue Yan
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Paper Abstract

Beta-carotene 100 mg/kg per day or vitamin C 50 mg/kg per day was administered orally for two days and did not prevent mouse skin photosensitization caused by hematoporphyrin derivative (HpD). However, (beta) -carotene 100 mg/kg per day administered intramuscularly for two days prevented mouse skin reaction. Cimetidine and benadryl 10 mg/kg per day, P.O.X 2, effectively prevented mouse skin reaction. This suggests histamine may be involved in skin photoreaction induced by HpD.

Paper Details

Date Published: 5 March 1993
PDF: 3 pages
Proc. SPIE 1616, International Conference on Photodynamic Therapy and Laser Medicine, (5 March 1993); doi: 10.1117/12.137018
Show Author Affiliations
Nai-wu Fu, Cancer Institute (China)
Li-xue Yan, Cancer Institute (China)

Published in SPIE Proceedings Vol. 1616:
International Conference on Photodynamic Therapy and Laser Medicine
Junheng Li M.D., Editor(s)

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