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Journal of Biomedical Optics • Open Access

Photoacoustic computed tomography correcting for heterogeneity and attenuation
Author(s): Chao Huang; Liming Nie; Robert W. Schoonover; Lihong V. Wang; Mark A. Anastasio

Paper Abstract

We report an investigation of image reconstruction in photoacoustic tomography for objects that possess heterogeneous material and acoustic attenuation distributions. When the object contains materials, such as bone and soft-tissue, that are modeled using power law attenuation models with distinct exponents, we demonstrate that the effects of acoustic attenuation due to the most strongly attenuating material can be compensated for if the attenuation of the other less attenuating material(s) are neglected. Experiments with phantom objects are presented to validated our findings.

Paper Details

Date Published: 7 May 2012
PDF: 6 pages
J. Biomed. Opt. 17(6) 061211 doi: 10.1117/1.JBO.17.6.061211
Published in: Journal of Biomedical Optics Volume 17, Issue 6
Show Author Affiliations
Chao Huang, Washington Univ. in St. Louis (United States)
Liming Nie, Washington Univ. in St. Louis (United States)
Robert W. Schoonover, Washington Univ. in St. Louis (United States)
Lihong V. Wang, Washington Univ. in St. Louis (United States)
Mark A. Anastasio, Washington Univ. in St. Louis (United States)

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