The Moscone Center
San Francisco, California, United States
6 - 11 March 2021
Conference 11649
Three-Dimensional and Multidimensional Microscopy: Image Acquisition and Processing XXVIII
Conference Committee
Additional Conference Information
Chair Emeritus: Carol J. Cogswell, Univ. of Colorado Boulder (United States)




Call for Papers Flyer (341KB)
Thursday 3 December Show All Abstracts
Session 1: Multidimensional Fluorescence Imaging
Large-scale high-resolution 3D fluorescence imaging with a computational miniature mesoscope
Paper 11649-17
Author(s): Yujia Xue, Ian G. Davison, David A. Boas, Lei Tian, Boston Univ. (United States)
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Hyperspectral imaging approaches to characterize the distribution and expression of FRET in tissues isolated from a novel transgenic rat expressing a FRET-based probe
Paper 11649-42
Author(s): Naga Annamdevula, Univ. of South Alabama (United States)
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Time-resolved multi-spectral wide-field fluorescence lifetime imaging microscopy with a SPAD array detector
Paper 11649-26
Author(s): Alberto Ghezzi, Andrea Farina, Politecnico di Milano (Italy), CNR-Istituto di Fotonica e Nanotecnologie (Italy); Andrea Bassi, Gianluca Valentini, Ivan Rech, Giulia Acconcia, Ivan Labanca, Politecnico di Milano (Italy); Cosimo D'Andrea, Politecnico di Milano (Italy), Ctr. for Nano Science and Technology, Istituto Italiano di Tecnologia (Italy)
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Single-shot high-contrast multiplane imaging with a z-splitter prism
Paper 11649-36
Author(s): Sheng Xiao, Howard Gritton, Hua-an Tseng, Dana Zemel, Xue Han, Jerome Mertz, Boston Univ. (United States)
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FlimTK: a Python-based toolkit package for fluorescence lifetime imaging microscopy (FLIM) data analysis
Paper 11649-20
Author(s): Jindou Shi, Mantas Žurauskas, Prabuddha Mukherjee, Beckman Institute for Advanced Science and Technology (United States), GSK Ctr. for Optical Molecular Imaging (United States); Aneesh Alex, GlaxoSmithKline (United States), GSK Ctr. for Optical Molecular Imaging (United States); Darold Spillman, Marina Marjanovic, Beckman Institute for Advanced Science and Technology (United States), GSK Ctr. for Optical Molecular Imaging (United States); Steve R. Hood, GlaxoSmithKline (United States), GSK Ctr. for Optical Molecular Imaging (United States); Stephen A. Boppart, Beckman Institute for Advanced Science and Technology (United States), GSK Ctr. for Optical Molecular Imaging (United States), Univ. of Illinois (United States)
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Session 2: Super-Resolution Microscopy
Three-dimensional super-resolution microscopy in thicker specimens using adaptive optics (Invited Paper)
Paper 11649-46
Author(s): Martin J. Booth, Univ of Oxford (United Kingdom)
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Limitations of Fourier ring correlation as an image resolution metric
Paper 11649-48
Author(s): Erik K. Johnson, Stephen Becker, Carol Cogswell, Jian Xing, Simeng Chen, University of Colorado Boulder (United States)
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3D SPARCOM: sparsity-based approach for super-resolution microscopy from correlation information of high emitter-density frames
Paper 11649-10
Author(s): Gili Dardikman-Yoffe, Yonina C. Eldar, Weizmann Institute of Science (Israel)
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Session 3: Image Formation and Analysis I
Quantitative phase imaging-based machine learning approaches for the analysis of adherent and suspended cells
Paper 11649-19
Author(s): Björn Kemper, Westfälische Wilhelms-Univ. Münster (Germany); Hanna Eilers, Tilmann Klein, Klaus Brinker, Hochschule Hamm-Lippstadt (Germany); Steffi Ketelhut, Westfälische Wilhelms-Univ. Münster (Germany)
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Snapshot 3D imaging with a gigapixel-scale multi-aperture microscope
Paper 11649-6
Author(s): Kevin C. Zhou, Colin Cooke, Duke Univ. (United States); Jaehee Park, Ramona Optics, Inc. (United States); Pavan Konda, Duke Univ. (United States); Mark Harfouche, Ramona Optics, Inc. (United States); Roarke Horstmeyer, Duke Univ. (United States)
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Four-dimensional image formation theory of all laser microscopy including optical coherence tomography
Paper 11649-2
Author(s): Naoki Fukutake, Nikon Corp. (Japan); Yoshiaki Yasuno, Univ. of Tsukuba (Japan)
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fitting approach for eliminating scattered light
Paper 11649-47
Author(s): Sabrina Civale, Northeastern University (United States)
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Session 4: Image Analysis and Deep Learning
Deep learning framework applied to optical diffraction tomography (ODT)
Paper 11649-37
Author(s): William Pierré, Lionel Hervé, Cédric Allier, Sophie Morales, CEA (France); Sergei Grudinin, Institut National de Recherche en Informatique et en Automatique (France); Shwetadwip Chowdhury, Laura Waller, Univ. of California, Berkeley (United States)
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Deep-learning-based Volumetric Imaging in Fluorescence Microscopy
Paper 11649-35
Author(s): Luzhe Huang, Yilin Luo, Yair Rivenson, Aydogan Ozcan, UCLA Samueli School of Engineering (United States)
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Towards generalizable neural networks for reconstruction problems: A look at Hyper-spectral Image Reconstruction
Paper 11649-30
Author(s): Eddie M. Gil, Mark Keppler, Texas A&M Univ. (United States), SAIC (United States); Vladislav V. Yakovlev, Texas A&M Univ. (United States); Joel Bixler, Air Force Research Lab. (United States)
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automatic nuclei Segmentation based on fuzzy C-Mean
Paper 11649-1
Author(s): Saif Hussein, The Univ. of Buckingham (United Kingdom), Univ. of Baghdad (Iraq)
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Session 5: Innovations in Optical Design
Optical design for high accuracy and precision in polarized super resolution imaging (Invited Paper)
Paper 11649-29
Author(s): Sophie Brasselet, Institut Fresnel (France)
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Solid immersion meniscus lens (SIMlens) enables multi-resolution open-top light-sheet microscopy
Paper 11649-4
Author(s): Lindsey Barner, Adam K. Glaser, Hongyi Huang, Jonathan T. C. Liu, Univ. of Washington (United States)
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Large field-of-view three-dimensional imaging with low computational complexity using random microlens array
Paper 11649-21
Author(s): Feng Tian, Junjie Hu, Weijian Yang, Univ. of California, Davis (United States)
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Evaluation of different illumination designs for tunable 3D structured illumination microscopy through model-based restoration
Paper 11649-49
Author(s): Jules Mohammed, Chrysanthe Preza, Cong Tuan S. Van, The Univ. of Memphis (United States)
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High-throughput 3D imaging with compressive lens-free tomography
Paper 11649-23
Author(s): Zhenxiang Luo, Abdulkadir Yurt, Andy Lambrechts, Dries Braeken, Liesbet Lagae, imec (Belgium)
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Session 6: New Methods in Illumination
Hybrid open-top light-sheet microscopy for 3D imaging of cleared tissues with mesoscopic and sub-micron resolution
Paper 11649-18
Author(s): Adam K. Glaser, Jonathan T. C. Liu, Univ. of Washington (United States)
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Intensity uniformity optimization in spatial light modulator-based multifocal microscope
Paper 11649-32
Author(s): Muhammad Junaid Amin, Sabine Petry, Haw Yang, Joshua W. Shaevitz, Princeton Univ. (United States)
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using engineered point spread functions to enable extended depth of field imaging for inexpensive 3D high throughput clinical testing
Paper 11649-33
Author(s): Anurag Agrawal, Warren Colomb, Scott Gaumer, Double Helix Optics (United States)
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Single- and dual-objective light-sheet microscope architectures for cleared tissues: a simulation-based performance comparison
Paper 11649-11
Author(s): Kevin W. Bishop, Adam K. Glaser, Jonathan T. C. Liu, Univ. of Washington (United States)
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Spatial light modulator approaches for reducing scattered and out-of-focus light
Paper 11649-45
Author(s): Samuel H. Chung, Northeastern Univ. (United States)
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Session 7: Molecules, Particles and Orientational Imaging
Birefringent Fourier filtering for single molecule coordinate and height super-resolution imaging with dithering and orientation
Paper 11649-50
Author(s): Valentina Curcio, Luis A. Alemán Castañeda, Institut Fresnel (France); Thomas G. Brown, The Institute of Optics, Univ. of Rochester (United States); Sophie Brasselet, Miguel A. Alonso, Institut Fresnel (France)
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Camera-based single-particle orientation imaging of quantum dots
Paper 11649-5
Author(s): Duncan Ryan, Los Alamos National Lab. (United States)
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Method for measurement of collagen monomer orientation in fluorescence microscopy
Paper 11649-38
Author(s): Rodrigo P. Alzola, Jose Delpiano, Univ. de los Andes (Chile); Anuj Gajjar, Rickard Stureborg, Seyed M. Siadat, Jeffrey W. Ruberti, Charles A. DiMarzio, Northeastern Univ. (United States)
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Session 8: Image Formation and Analysis II
Reconstructing refractive index of 3D multiple-scattering phantom from incoherent fluorescence images
Paper 11649-34
Author(s): Yi Xue, Univ. of California, Berkeley (United States)
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Auto-correlation for multi-view deconvolved reconstruction in light sheet microscopy
Paper 11649-39
Author(s): Daniele Ancora, Politecnico di Milano (Italy); Gianluca Valentini, Antonio Giovanni Pifferi, Andrea Bassi, Politecnico di Milano (Italy), CNR-Istituto di Fotonica e Nanotecnologie (Italy)
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Computed optical coherence tomography
Paper 11649-41
Author(s): Xuan Liu, New Jersey Institute of Technology (United States); Yuan Xin, Nokia Bell Labs (United States)
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Session 9: Quantitative Imaging of Biological Systems
Three-dimensional quantification of cerebral vasculature in mouse brains with confocal microscopy
Paper 11649-22
Author(s): Danny Xie, Christian Crouzet, Katiana Khouri, Krystal LoPresti, Yuke Wang, Christopher Robinson, David Cribbs, Mark Fisher, Bernard Choi, Univ. of California, Irvine (United States)
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3D imaging of the vagus nerve fascicular anatomy with cryo-imaging and UV excitation
Paper 11649-7
Author(s): Chaitanya Kolluru, Ananya Subramaniam, Yehe Liu, Aniruddha Upadhye, Monty Khela, Lindsey Druschel, Case Western Reserve Univ. (United States); Farzad Fereidouni, Richard Levenson, Univ. of California, Davis (United States); Andrew Shoffstall, Michael Jenkins, David Wilson, Case Western Reserve Univ. (United States)
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Single-cell analysis pipeline for quantification of intracellular drug distribution by CARS/2PF/FLIM
Paper 11649-8
Author(s): Jindou Shi, Beckman Institute for Advanced Science and Technology (United States), GSK Ctr. for Optical Molecular Imaging (United States); Prabuddha Mukherjee, GSK Ctr. for Optical Molecular Imaging (United States), Beckman Institute for Advanced Science and Technology (United States); Aneesh Alex, GlaxoSmithKline (United States), GSK Ctr. for Optical Molecular Imaging (United States); Edita Aksamitiene, GSK Ctr. for Optical Molecular Imaging (United States), Beckman Institute for Advanced Science and Technology, Univ. of Illinois (United States); Darold Spillman, Beckman Institute for Advanced Science and Technology (United States), GSK Ctr. for Optical Molecular Imaging (United States); Marina Marjanovic, Carle Illinois College of Medicine, Univ. of Illinois (United States), GSK Ctr. for Optical Molecular Imaging (United States); Minh Doan, GlaxoSmithKline (United States); Steve R. Hood, GlaxoSmithKline (United Kingdom), GSK Ctr. for Optical Molecular Imaging (United States); Stephen A. Boppart, Beckman Institute for Advanced Science and Technology (United States), GSK Ctr. for Optical Molecular Imaging (United States), Univ. of Illinois (United States)
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Optimized optical clearing method for making 3D virtual H&E stained images using light sheet fluorescence microscopy
Paper 11649-40
Author(s): Inkeon Ryu, Daekeun Kim, Dankook Univ. (Korea, Republic of)
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Session 10: User Interfaces & Visualization
Visualizing the full depth of the human uterine wall through three-dimensional mosaic Optical Coherence Tomography
Paper 11649-14
Author(s): Isaac C. Donis, James P. McLean, Christine P. Hendon, Columbia Univ. (United States)
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Jolab a free and open-source software to simulate light propagation in optical systems
Paper 11649-16
Author(s): Dylan Marques, James A. Guggenheim, Peter R. T. Munro, Univ. College London (United Kingdom)
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DOF adjustment and 3D free viewpoint viewing of Z stack data of fluorescent microscope using image processing
Paper 11649-13
Author(s): Tsuneyuki Hagiwara, Nikon Corp. (Japan)
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Session P: Poster Session
Compressive fluorescence microscopy
Paper 11649-24
Author(s): Payvand Arjmand, Saints-Pères Paris Institute for the Neurosciences (France)
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Real-time optical flow sensing with SD-OCT: towards a modular motion-correction platform for microscopy
Paper 11649-25
Author(s): Stephen Tucker, Michael Wallace, Jianbo Tang, Anderson Chen, David A. Boas, Boston Univ. (United States)
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Non-orthogonal dual-objective light-sheet microscopy for subcellular imaging of cleared tissues
Paper 11649-31
Author(s): Kevin W. Bishop, Robert Serafin, Adam K. Glaser, Univ. of Washington (United States); Philip R. Nicovich, Allen Institute for Brain Science (United States); Jonathan T. C. Liu, Univ. of Washington (United States)
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Effects of tissue autofluorescence on FRET efficiency estimates
Paper 11649-43
Author(s): D.J. Pleshinger, Naga Annamdevula, Silas J. Leavesley, Tom C. Rich, Univ. of South Alabama (United States)
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