The Moscone Center
San Francisco, California, United States
23 - 28 January 2021
Conference BO602
Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XIII
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Abstract Due:
15 July 2020

Author Notification:
21 September 2020

Manuscript Due Date:
5 January 2021

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Conference Chairs
Program Committee
Program Committee continued...
  • Hisataka Kobayashi, National Cancer Institute (United States)
  • Dolonchampa Maji, Washington Univ. School of Medicine in St. Louis (United States)
  • Ashok Kumar Mishra, Indian Institute of Technology Madras (India)
  • Gabor Patonay, Georgia State Univ. (United States)
  • Attila Tarnok, Univ. Leipzig (Germany)
  • Deepa Venkitesh, Indian Institute of Technology Madras (India)

Call for

Submissions to this conference may include the following to improve the chance for acceptance:
  • 100-word text abstract (for online program)
  • 250-word text abstract (for abstract digest)
  • Optional 2-page extended abstract (for committee review only). The extended abstract must be submitted as a separate PDF document limited to two pages, including tables and figures. Include author names and affiliations; text; any figures, tables, or images; and sufficient data to permit committee review.
All submissions will be reviewed by the Program Committee to determine acceptance. Extended abstracts will be used only for the purpose of review, and will not be published.

Chemical and genetic sensors, reporters, and molecular probes are the cardinal elements in molecular imaging and analyses of normal and pathophysiological processes at the cellular and molecular levels. Diverse molecular designs with unique optical signatures have been developed and are currently used to sense the presence and activity of molecular targets that characterize specific biological processes. These have been used to probe human diseases, explore the mechanisms of pathogenesis, monitor drug efficacy, discriminate healthy from diseased tissues, and assess therapeutic outcomes. These applications deploy molecular probes over a range of scales from microscopy and subcelluar resolution to optical tomography of entire organisms. Development and use of these probes typically involve multidisciplinary teams that have assembled to address specific biological questions.

The objective of this conference is to provide a forum to present and collate significant and exciting studies involving chemically or biologically developed optical molecular probes that have been used in biomedical research. Papers appropriate for this solicitation include, but are not limited to studies performed with dyes, bioluminescent enzymes, photoproteins such as GFP, activatable probes, receptor-, tissue-, or function-specific probes, nonspecific contrast effectors, nanoparticles, quantum dots, and multimodal molecular probes, monitoring molecular and physiological processes in cell and living organisms, clinical use of imaging agents, and applications of biomarkers and sensors in medicine and biology. This conference will target state-of-the-art studies where these probes have been used, in vitro or in vivo, and encompasses a wide variety of applications. To accommodate the multidisciplinary nature of the conference, papers are requested from a variety of subject areas, including the following topics:

Design, synthesis, development, or analyses of near-infrared and other fluorescent dyes
  • novel dyes (fluorescent, absorption, and environment-sensitive dyes)
  • novel luminescent probes
  • absorption-, fluorescent-, and light scattering-based agents
Design, synthesis, development, and analyses of nanoparticles
  • caged complexes or chelated optical markers
  • quantum dots, micro- and nanoparticles
Development of bioluminescence and fluorescent proteins, intrinsic probes, and molecular reporters
  • function-specific chemical and biological sensors
  • molecular beacons
Markers for membrane potential, electrolytes, and pH regulations
  • structure-dependent spectroscopy
  • intracellular and extracellular pH measurements
  • functional analysis of biological processes in cells and animals
In vitro and in vivo applications of contrast agents and molecular probes
  • genomics and proteomics, including gene expression biological assays, including immunoassays, cell internalization, receptor binding, LRET, FRET and FISH studies
  • physiologic function monitoring, including molecular and cellular events, pH, electrolytes, metabolites, minerals, and membrane potential
  • in vivo organ function monitoring
  • molecular, cellular, and tissue imaging
  • site-specific delivery mechanisms and endoscopy methods
  • multicolor and multimodality imaging systems and upconversion markers
  • real-time monitoring of disease progression or regression
  • tandem diagnostic and therapeutic interventions
  • molecular ruler design and application
  • monitoring treatment response
  • contrast agents for imaging applications
Time-resolved tissue spectroscopy for medical diagnosis and imaging
  • fluorescence lifetime spectroscopy and imaging
  • fluorescence lifetime of endogenous and exogenous fluorescent materials and molecules
  • time-resolved fluorescence methods based on endogenous and exogenous molecules
  • new disease biomarkers
  • imaging disease biomarkers
  • methods for identify and amplify signals for imaging biomarkers
Pathway to clinical translation of imaging probes and nanomaterials
  • human studies using imaging agents
  • challenges of human translational studies with contrast agents and optical probes
  • regulatory issues related to human studies by optical methods.
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