The Moscone Center
San Francisco, California, United States
2 - 7 February 2019
Conference 10860
Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XXVIII
Saturday - Sunday 2 - 3 February 2019
Important
Dates
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Abstract Due:
25 July 2018

Author Notification:
1 October 2018

Manuscript Due Date:
11 January 2019

Conference
Committee
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Conference Chairs
Program Committee
Additional Conference
Information
This meeting is dedicated to our friend, Thomas Dougherty, a pioneer in the field of photodynamic therapy.
Saturday 2 February Show All Abstracts
Session 1:
Photodynamic Therapy I
Saturday 2 February 2019
9:00 AM - 10:00 AM
Location: Room 307 (South Level Three)
Session Chair:
David H. Kessel, Wayne State Univ. (United States)
Photodynamic therapy and paraptosis: an update
Paper 10860-1
Time: 9:00 AM - 9:30 AM
Author(s): David H. Kessel, Wayne State Univ. (United States)
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Does PDT have a special niche as an affordable technology?
Paper 10860-2
Time: 9:30 AM - 10:00 AM
Author(s): Tayyaba Hasan, Wellman Ctr. for Photomedicine (United States)
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Coffee Break 10:00 AM - 10:30 AM
Session 2:
Photodynamic Therapy II
Saturday 2 February 2019
10:30 AM - 11:30 AM
Location: Room 307 (South Level Three)
Session Chair:
Jonathan P. Celli, Univ. of Massachusetts Boston (United States)
Targeting drug-resistant glioblastoma stem cells using photodynamic therapy
Paper 10860-3
Time: 10:30 AM - 10:50 AM
Author(s): Bryan Q. Spring, Northeastern Univ. (United States); Kohei Watanabe, Wellman Ctr. for Photomedicine (United States), Canon U.S.A., Inc. (United States); Megumi Ichikawa, Srivalleesha Mallidi, Tatsuyuki Matsudaira, Dmitriy Timerman, Wellman Ctr. for Photomedicine (United States); Hiroaki Wakimoto, Massachusetts General Hospital (United States), Harvard Medical School (United States); Tayyaba Hasan, Wellman Ctr. for Photomedicine (United States), Massachusetts General Hospital (United States), Harvard Medical School (United States)
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Chemically tuned NIR activatable nanoconstructs selectively destroy pancreatic tumor cells in a desmoplastic heterocellular 3D model
Paper 10860-4
Time: 10:50 AM - 11:10 AM
Author(s): Girgis Obaid, Shazia Bano, Srivalleesha Mallidi, Wellman Ctr. for Photomedicine (United States); Diane Simeone, Perlmutter Cancer Ctr. (United States); Tayyaba Hasan, Wellman Ctr. for Photomedicine (United States)
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Overcoming chemoresistance using tumor mitochondria-targeted photodynamic therapy
Paper 10860-5
Time: 11:10 AM - 11:30 AM
Author(s): Yang Liu, Jing Cui, Meng Su, Dawei Zhang, Mingfeng Bai, Vanderbilt Univ. Medical Ctr. (United States)
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Lunch/Exhibition Break 11:30 AM - 2:00 PM
Session 3:
Photodynamic Therapy III
Saturday 2 February 2019
2:00 PM - 3:00 PM
Location: Room 307 (South Level Three)
Session Chair:
Theresa M. Busch, Univ. of Pennsylvania (United States)
Looking to the innate immune system for imageable biomarkers of PDT response
Paper 10860-6
Time: 2:00 PM - 2:20 PM
Author(s): Theresa M. Busch, Univ. of Pennsylvania (United States)
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Comparison of finite element modeling and Monte Carlo simulations for interstitial photodynamic therapy
Paper 10860-7
Time: 2:20 PM - 2:40 PM
Author(s): Emily Oakley, Roswell Park Comprehensive Cancer Ctr. (United States); Angelica Manalac, Princess Margaret Cancer Ctr. (Canada), Univ. of Toronto (Canada); Jeffrey Cassidy, Univ. of Toronto (Canada); Lothar D. Lilge, Princess Margaret Cancer Ctr. (Canada), Univ. of Toronto (Canada); Gal Shafirstein, Roswell Park Comprehensive Cancer Ctr. (United States)
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Nuclear targeted x-ray activated photodynamic therapy: a solution to treat pancreatic cancer
Paper 10860-8
Time: 2:40 PM - 3:00 PM
Author(s): Sandhya Clement, Ayad Anwer, Wei Deng, The Univ. of New South Wales (Australia); Brian C. Wilson, Christine Allen, Univ. of Toronto (Canada); Ewa M. Goldys, The Univ. of New South Wales (Australia)
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Coffee Break 3:00 PM - 3:30 PM
Session 4:
Photodynamic Therapy IV
Saturday 2 February 2019
3:30 PM - 5:10 PM
Location: Room 307 (South Level Three)
Session Chair:
Timothy C. Zhu, Perelman Ctr. for Advanced Medicine (United States)
Combining Raman spectroscopy and photodynamic therapy for optical cancer theranostics
Paper 10860-9
Time: 3:30 PM - 3:50 PM
Author(s): Conor C. Horgan, Mads S. Bergholt, Anika Nagelkerke, Isaac J. Pence, Ulrike Kauscher, Molly M. Stevens, Imperial College London (United Kingdom)
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Tolerating uncertainty: photodynamic therapy planning with optical property variation
Paper 10860-10
Time: 3:50 PM - 4:10 PM
Author(s): Abdul-Amir Yassine, Univ. of Toronto (Canada); Lothar D. Lilge, Univ. of Toronto (Canada), Princess Margaret Cancer Research Ctr. (Canada); Vaughn Betz, Univ. of Toronto (Canada)
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Fluorescence imaging of photosensitizers in biological tissues for photodynamic diagnosis during interstitial photodynamic therapy
Paper 10860-11
Time: 4:10 PM - 4:30 PM
Author(s): Takahiro Nishimura, Kunio Awazu, Osaka Univ. (Japan)
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Validation of tissue optical properties measurement using diffuse reflectance spectroscopy (DRS)
Paper 10860-12
Time: 4:30 PM - 4:50 PM
Author(s): Yi Hong Ong, Yihua Zhu, Timothy C. Zhu, Perelman Ctr. for Advanced Medicine (United States)
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Analysis of cumulative surface dose based on Cherenkov imaging of Total Skin Electron Therapy (TSET)
Paper 10860-13
Time: 4:50 PM - 5:10 PM
Author(s): Heather Petroccia, Perelman Ctr. for Advanced Medicine (United States); Tianshun Miao, Thayer School of Engineering at Dartmouth (United States); Amit Maity, Yi Hong Ong, Yihua Zhu, Perelman Ctr. for Advanced Medicine (United States); Petr Bruza, Brian W. Pogue, Thayer School of Engineering at Dartmouth (United States); John Plastaras, Timothy C. Zhu, Perelman Ctr. for Advanced Medicine (United States)
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Session PSat:
Posters-Saturday
Saturday 2 February 2019
5:15 PM - 6:45 PM
Location: InterContinental Hotel, Grand Ballroom (3rd Floor) & InterContinental Ballroom (5th Floor)

Conference attendees are invited to attend the BiOS poster session on Saturday evening. Come view the posters, enjoy light refreshments, ask questions, and network with colleagues in your field.

Poster Setup: Saturday 10:00 AM – 4:30 PM
View poster presentation guidelines and set-up instructions at
http://spie.org/PWPosterGuidelines
Assembly of a PDT device with a near-infrared fluorescence monitoring of PpIX during treatment
Paper 10860-28
Time: 5:15 PM - 6:45 PM
Author(s): Marlon R. Garcia, Sebastião Pratavieira, Lilian T. Moriyama, Cristina Kurachi, Daniel V. Magalhães, Univ. de São Paulo (Brazil)
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Membrane fusogenic liposomes loaded with PpIX for photodynamic therapy
Paper 10860-29
Time: 5:15 PM - 6:45 PM
Author(s): Ilaiáli Souza Leite, Instituto de Física de São Carlos (Brazil); Gabriela Mayr Reyes, Instituto de Química de São Carlos (Brazil); Juliana Cancino-Bernardi, Natalia M. Inada, Instituto de Física de São Carlos (Brazil)
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Reactive oxygen species explicit dosimetry to predict tumor growth for BPD-mediated vascular photodynamic therapy
Paper 10860-30
Time: 5:15 PM - 6:45 PM
Author(s): Tianqi Sheng, Yi Hong Ong, Theresa Busch, Timothy C. Zhu, Univ. of Pennsylvania (United States)
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Multi-session PDT in 3D cell culture of breast cancer
Paper 10860-31
Time: 5:15 PM - 6:45 PM
Author(s): Carolina P. Campos, Ievgeniia Iermak, Natalia M. Inada, Cristina Kurachi, Univ. de São Paulo (Brazil)
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AAPM TG 274 recommendations for in-vivo light dosimetry for PDT
Paper 10860-32
Time: 5:15 PM - 6:45 PM
Author(s): Timothy C. Zhu, Univ. of Pennsylvania Health System (United States); Andrea Dimofte, Jarod C. Finlay, Univ. of Pennsylvania Health System (United States); Lothar D. Lilge, Univ. Health Network (Canada); Brian W. Pogue, Dartmouth College (United States); Robert van Veen, Univ. Medical Ctr. Utrecht (Netherlands); Marla Dowell, National Institute of Standards and Technology (United States); Valdir Colussi, UH Case Seidman Cancer Ctr. (United States); Ulas Sunar, Wright State Univ. (United States); Charles Simone, Univ. of Maryland School of Medicine (United States)
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Evaluation of stability and comfort of applicators for photodynamic therapy of oral cavity tumors
Paper 10860-34
Time: 5:15 PM - 6:45 PM
Author(s): Srivalleesha Mallidi, Wellman Ctr for Photomedicine (United States); Hui Liu, University of Massachusetts Boston (United States); Amjad Khan, Tayyaba Hasan, Wellman Ctr for Photomedicine (United States); Jonthan Celli, University of Massachusetts Boston (United States)
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BiOS Hot Topics
Saturday 2 February 2019
7:00 PM - 9:00 PM
Location: Room 206/214 (South Level Two)
Sunday 3 February Show All Abstracts
Session 5:
Photodynamic Therapy V
Sunday 3 February 2019
9:10 AM - 10:00 AM
Location: Room 307 (South Level Three)
Session Chair:
Kenneth K. Wang, Mayo Clinic (United States)
Photodynamic therapy produces more durable response than radiofrequency ablation for the treatment of Barrett's esophagus
Paper 10860-14
Time: 9:10 AM - 9:40 AM
Author(s): Kenneth K. Wang, Juan Genere, Lori Lutzke, Bryan Linn, Kristyn Maixner, Cadman Leggett, Mayo Clinic (United States)
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Potential role of vitamin D as a biological enhancer for photodynamic therapy (PDT) of skin cancer and precancer: preliminary results from two clinical trials
Paper 10860-15
Time: 9:40 AM - 10:00 AM
Author(s): Edward V. Maytin, Lerner Research Institute - Cleveland Clinic (United States); Christine B. Warren, Urvashi Kaw, Judith Mack, The Cleveland Clinic (United States); Taylor Bullock, Lerner Research Institute - Cleveland Clinic (United States)
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Coffee Break 10:00 AM - 10:30 AM
Session 6:
Photodynamic Therapy VI
Sunday 3 February 2019
10:30 AM - 11:40 AM
Location: Room 307 (South Level Three)
Session Chair:
Edward V. Maytin, Lerner Research Institute - Cleveland Clinic (United States)
Photodynamic therapy for the treatment of locally advanced pancreatic cancer
Paper 10860-16
Time: 10:30 AM - 11:00 AM
Author(s): Kenneth K. Wang, Cadman Leggett, Bryan Linn, Juan Genere, Roy Bhaskar, Mayo Clinic (United States)
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PDT photo activation irradiance monitoring during a Phase I clinical study of TLD1433 in bladder cancer
Paper 10860-17
Time: 11:00 AM - 11:20 AM
Author(s): Lothar D. Lilge, Jenny Wu, Angelica Manalac, Univ. Health Network (Canada); Jeffrey Cassidy, Univ. of Toronto (Canada); Wayne Embree, Theralase Inc. (Canada); Roger White, Arkady Mandel, Theralase, Inc. (Canada); Vaughn Betz, Univ. of Toronto (Canada); Michael Jewett, Girish Kulkarni, Univ. Health Network (Canada)
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Methylene blue photodynamic therapy for treatment of deep tissue abscess cavities
Paper 10860-18
Time: 11:20 AM - 11:40 AM
Author(s): Timothy M. Baran, Univ. of Rochester Medical Ctr. (United States); Mattison J. Flakus, Hyun W. Choi, Univ. of Rochester (United States)
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Lunch/Exhibition Break 11:40 AM - 1:40 PM
Session 7:
Photodynamic Therapy VII
Sunday 3 February 2019
1:40 PM - 3:00 PM
Location: Room 307 (South Level Three)
Session Chair:
Bryan Q. Spring, Northeastern Univ. (United States)
Painless versus conventional photodynamic therapy for treatment of actinic keratosis: comparison of cell death and immune response in a murine model
Paper 10860-19
Time: 1:40 PM - 2:00 PM
Author(s): Sanjay Anand, Anton Yasinchak, Mukul Govande, The Cleveland Clinic (United States); Sajina Shakya, Cleveland Clinic (United States); Edward V. Maytin, The Cleveland Clinic (United States)
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Personalized strategies for delivering photo therapies to solid tumors with theranostic nanoparticles
Paper 10860-20
Time: 2:00 PM - 2:20 PM
Author(s): Amit Joshi, Medical College of Wisconsin (United States)
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Controlled drug release from a X-ray triggered liposomal delivery platform for colorectal cancer treatment
Paper 10860-21
Time: 2:20 PM - 2:40 PM
Author(s): Wei Deng, The Univ. of New South Wales (Australia); Wenjie Chen, Macquarie Univ. (Australia); Sandhya Clement, Anna Guller, The Univ. of New South Wales (Australia); Zhenjun Zhao, Macquarie Univ. (Australia); Alexander Engel, The Univ. of Sydney (Australia); Ewa M. Goldys, The Univ. of New South Wales (Australia)
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Validation of Dosie combined Monte Carlo and photokinetic simulations for the analysis of HPPH-mediated photodynamic therapy on mice
Paper 10860-22
Time: 2:40 PM - 3:00 PM
Author(s): Karl Beeson, Evgueni Parilov, Mary J. Potasek, Simphotek Inc. (United States)
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Coffee Break 3:00 PM - 3:30 PM
Session 8:
Photodynamic Therapy VIII
Sunday 3 February 2019
3:30 PM - 5:10 PM
Location: Room 307 (South Level Three)
Session Chair:
Srivalleesha Mallidi, Wellman Ctr. for Photomedicine (United States)
A 2D imaging dosimeter for photodynamic therapy
Paper 10860-23
Time: 3:30 PM - 3:50 PM
Author(s): M. Hinds, T. Moritz, Physical Sciences Inc. (United States); Jason R. Gunn, Brian W. Pogue, Dartmouth College (United States); Steven J. Davis, Physical Sciences Inc. (United States)
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Modifying pancreatic tumor stroma stiffness to improve vascular perfusion and verteporfin delivery with angiotensin II receptor blockers
Paper 10860-24
Time: 3:50 PM - 4:10 PM
Author(s): Phuong Vincent, Jason R. Gunn, Kayla Marra, Kimberley Samkoe, P. Jack Hoopes, Thayer School of Engineering at Dartmouth (United States); Tayyaba Hasan, Wellman Ctr. for Photomedicine (United States); Brian W. Pogue, Thayer School of Engineering at Dartmouth (United States)
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Modeling PpIX-effective fluence rate in tissue for multiple light sources used in photodynamic therapy of skin
Paper 10860-25
Time: 4:10 PM - 4:30 PM
Author(s): Ethan Philip M. LaRochelle, Kayla Marra, Thayer School of Engineering at Dartmouth (United States); Robert E. LeBlanc, Michael S. Chapman, Geisel School of Medicine, Dartmouth College (United States); Edward V. Maytin, Cleveland Clinic (United States); Tayyaba Hasan, Wellman Ctr. for Photomedicine (United States), Massachusetts General Hospital (United States), Harvard Medical School (United States); Brian W. Pogue, Thayer School of Engineering at Dartmouth (United States)
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Smartphone-based imaging system for individualization of PDT treatment planning for protoporphyrin IX based skin cancer treatment
Paper 10860-26
Time: 4:30 PM - 4:50 PM
Author(s): Alberto J. Ruiz, Brian W. Pogue, Ethan Philip M. LaRochelle, Thayer School of Engineering at Dartmouth (United States)
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A platform for intraoral PDT light delivery using modular 3D printed components
Paper 10860-27
Time: 4:50 PM - 5:10 PM
Author(s): Hui Liu, Univ. of Massachusetts Boston (United States); Amjad Khan, Srivaleesha Mallidi, Massachusetts General Hospital (United States); Paola Leon, Grant Rudd, Liam Daly, Yiran Liu, Univ. of Massachusetts Boston (United States); Shakir Khan, Jawaharlal Nehru Medical College (India), Aligarh Muslim Univ. (India); Bilal Hussain, Aligarh Muslim Univ. (India), Jawaharlal Nehru Medical College (India); Shahid Siddiqui, Jawaharlal Nehru Medical College (India), Aligarh Muslim Univ. (India); Meredith August, Maria Troulis, Massachusetts General Hospital (United States); Colin Hopper, Stephen Bown, Univ. College London (United Kingdom); Filip Cuckov, Univ. of Massachusetts Boston (United States); Tayyaba Hasan, Massachusetts General Hospital (United States); Jonathan P. Celli, Univ. of Massachusetts Boston (United States)
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