The goal of this conference is to present novel, state-of-the-art work in non-invasive spectroscopic and imaging methods to detect the onset and progression of disease, including pre-malignancy and malignancy, and intra-operatively, and tissue and cells’ response to external conditions, including therapeutic intervention, unintended injury, and laser energy deposition. The conference will focus on work investigating the differences in single and multiphoton excitation optical signatures of normal and diseased tissues, and on understanding the underlying biochemical and structural changes of tissues and cells responsible for the observed spectroscopic signatures. There will also be a fast spectral data processing focus, with a view to real-time diagnostics through spectra, and including reservoir computing, biomimetic approaches, machine learning, and kernel methods, like SVMs (support-vector-machines). It is worth noting that this conference has hosted in recent years a number of contributions on the detection of disease using optical spectroscopy signatures of body fluids such as urine or blood plasma. As the field of metabolomics continues to grow, it is possible that “optical metabolomics” maybe a new frontier in the field of Optical Biopsy. Complex light, quantum effects and entanglement biomedical analysis of tissue, cells and structural components is a new thrust in Optical Biopsy.

This conference covers a wide array of well-established optical techniques and novel approaches to diagnose tissues changes, including in vivo and ex vivo fluorescence spectroscopy, Stokes shift spectroscopy, spectral imaging, Raman spectroscopy, Stimulated Raman, resonance Raman, multiphoton and photonic methods to modify the tissue and body fluid properties or functions implemented in vivo or ex-vivo covering the technology development steps from bench-to-bedside, at the point of need. Compact pill smart spectral explorers, multi-spectral imagers, coherence effects, and hyper-spectral imaging will be highlighted and covered, in part, by speakers.

Topics include: ;
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Conference BO306

Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis

This conference has an open call for papers:
Abstract Due: 20 July 2022
Author Notification: 10 October 2022
Manuscript Due: 11 January 2023
The goal of this conference is to present novel, state-of-the-art work in non-invasive spectroscopic and imaging methods to detect the onset and progression of disease, including pre-malignancy and malignancy, and intra-operatively, and tissue and cells’ response to external conditions, including therapeutic intervention, unintended injury, and laser energy deposition. The conference will focus on work investigating the differences in single and multiphoton excitation optical signatures of normal and diseased tissues, and on understanding the underlying biochemical and structural changes of tissues and cells responsible for the observed spectroscopic signatures. There will also be a fast spectral data processing focus, with a view to real-time diagnostics through spectra, and including reservoir computing, biomimetic approaches, machine learning, and kernel methods, like SVMs (support-vector-machines). It is worth noting that this conference has hosted in recent years a number of contributions on the detection of disease using optical spectroscopy signatures of body fluids such as urine or blood plasma. As the field of metabolomics continues to grow, it is possible that “optical metabolomics” maybe a new frontier in the field of Optical Biopsy. Complex light, quantum effects and entanglement biomedical analysis of tissue, cells and structural components is a new thrust in Optical Biopsy.

This conference covers a wide array of well-established optical techniques and novel approaches to diagnose tissues changes, including in vivo and ex vivo fluorescence spectroscopy, Stokes shift spectroscopy, spectral imaging, Raman spectroscopy, Stimulated Raman, resonance Raman, multiphoton and photonic methods to modify the tissue and body fluid properties or functions implemented in vivo or ex-vivo covering the technology development steps from bench-to-bedside, at the point of need. Compact pill smart spectral explorers, multi-spectral imagers, coherence effects, and hyper-spectral imaging will be highlighted and covered, in part, by speakers.

Topics include:
  • origin of tissue optical properties
  • optical methods for tissue diagnosis and treatment
  • methods for in vivo assessment of physiological state of tissue
  • excitation, absorption, fluorescence spectroscopy and imaging
  • Mid-infrared (MIR) absorption spectroscopy and hyperspectral imaging
  • Raman spectroscopy and imaging
  • Resonance Raman spectroscopy
  • inelastic light scattering spectroscopy and imaging
  • Stimulated Raman gain spectroscopy and imaging
  • polarization and diffusive reflectance spectral imaging
  • THz spectroscopy and imaging
  • photoluminescence spectroscopy and imaging
  • multi-photon spectroscopy and imaging
  • time resolved spectroscopy and imaging
  • speckle and spatial Fourier frequency spectroscopy for diagnoses
  • ultraviolet diagnostic methods
  • near-infrared (NIR) diagnostic methods
  • nano-particle tagging and contrast agents
  • chemo- and molecular targeting agents
  • instrumentation of in vivo optical biopsy
  • in vivo spectroscopy and imaging
  • optical processes at the single cell level
  • endoscopes and micro-endoscopes for optical biopsy: visible to THz
  • novel methods for optical biopsy
  • optical biopsy mapping with linear excitation methods
  • nonlinear optical biopsy mapping
  • novel coherence methods
  • instrumentation for in-vivo optical biopsy
  • video spectral imaging and mapping of tissue
  • STED nano-scale imaging
  • non-invasive detection and imaging of cancer
  • diabetes non-invasive detection
  • assessment of tissue injury
  • photonic applications in neuro-science
  • optical methods for brain diseases, Autism, Alzheimer
  • optical metabolomics
  • supercontinuum for medical and biological applications
  • Stokes shift spectroscopy
  • upper excite states for deeper penetration in tissue and brain
  • NIR optical windows in 700 nm to 2500nm
  • MIR optical window 3 µm to 25 µm
  • coherent and non- contact photo-acoustic imaging
  • tissue modification with light pulses
  • laser tissue welding and real time monitoring
  • Complex Vector Vortex light propagation and imaging
  • dynamics of laser-tissue interactions
  • integration of optical detection and therapy systems
  • high resolution imaging methods for in vivo pathology
  • rapid tissue microstructure imaging with intrinsic or extrinsic mechanisms
  • lipidomics
  • fluorescence lifetime imaging (FLIM)
  • phosphorescence lifetime imaging (PLIM)
  • FLIM of fast metabolic effects
  • NADH / FAD fluorescence
  • Clinical FLIM applications
  • advanced multiphoton imaging
  • in-vivo multiphoton tomography of human skin and others
  • in-vivo FLIM of the human retina
  • protein interaction
  • time-resolved spectroscopy
  • NEW event thrust on fast spectral data processing focus, with a view to real-time diagnostics through spectra, and including reservoir computing, biomimetic approaches, machine learning, and kernel methods, like SVMs (support-vector-machines) and AI.
  • NEW optical metabolomics detection
  • NEW complex light on tissues, cells and structures: quantum effects and entanglement
Conference Chair
The City College of New York (United States)
Conference Chair
Univ. of Rochester Laboratory for Laser Energetics (United States)
Conference Chair
The Univ. of Nottingham (United Kingdom)
Conference Co-Chair
Univ. of California, San Diego (United States)
Program Committee
Naval Medical Research Ctr. (United States)
Program Committee
National Institutes of Health (United States)
Program Committee
Johns Hopkins Univ. (United States), Tel Aviv Univ. (Israel)
Program Committee
Univ. of Rochester (United States)
Program Committee
National Univ. of Singapore (Singapore)
Program Committee
Physical Sciences Inc. (United States)
Program Committee
Univ. of Oulu (Finland), Aston University (United Kingdom)
Program Committee
Davinci Applied Technologies Inc. (United States)
Program Committee
Memorial Sloan-Kettering Cancer Ctr. (United States)
Program Committee
Cornell Univ. (United States)
Program Committee
Ganesan Singaravelu
Anna Univ., Chennai (India)
Program Committee
Binlin Wu
Southern Connecticut State Univ. (United States)
Program Committee
Hunter College (United States)
Program Committee
Univ. of Massachusetts Lowell (United States)
Program Committee
Corning Incorporated (United States)
Additional Information
What you will need to submit
  • Title
  • Author(s) information
  • Speaker biography
  • 250-word abstract for technical review
  • 100-word summary for the program
  • Keywords used in search for your paper (optional)
Note: Only original material should be submitted. Commercial papers, papers with no new research/development content, and papers with proprietary restrictions will not be accepted for presentation.