The Moscone Center
San Francisco, California, United States
27 January - 1 February 2018
Conference 10505
High-Speed Biomedical Imaging and Spectroscopy III: Toward Big Data Instrumentation and Management
Monday - Tuesday 29 - 30 January 2018
Conference
Committee
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Conference Chairs
Conference Co-Chairs
Program Committee
  • Steven G. Adie, Cornell Univ. (United States)
  • Mohammad Hossein Asghari, Univ. of California, Los Angeles (United States)
  • Hongwei Chen, Tsinghua Univ. (China)
  • Pei-Yu Eric Chiou, Univ. of California, Los Angeles (United States)
  • Shi-Wei Chu, National Taiwan Univ. (Taiwan)
  • Qionghai Dai, Tsinghua Univ. (China)
  • Mark Foster, Johns Hopkins Univ. (United States)
  • Katsumasa Fujita, Osaka Univ. (Japan)
  • Liang Gao, Univ. of Illinois at Urbana-Champaign (United States)
  • Elena Holden, Executive Strategic Advisory, Biotech and IVD (United States)
  • Chulhong Kim, Pohang Univ. of Science and Technology (Korea, Republic of)

Program Committee continued...
Monday 29 January Show All Abstracts
Introduction by Conference Chairs
Monday 29 January 2018
8:40 AM - 8:50 AM
Location: Room 2018 (West Level 2)
Session 1:
Computational Imaging
Monday 29 January 2018
8:50 AM - 10:00 AM
Location: Room 2018 (West Level 2)
Session Chair:
Kevin K. Tsia, The Univ. of Hong Kong (Hong Kong, China)
Fourier ptychography for parallel microscopy (Invited Paper)
Paper 10505-1
Time: 8:50 AM - 9:20 AM
Author(s): Changhuei Yang, California Institute of Technology (United States)
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Trillion-frame-per-second compressed ultrafast photography
Paper 10505-2
Time: 9:20 AM - 9:40 AM
Author(s): Jinyang Liang, Institut National de la Recherche Scientifique (Canada), California Institute of Technology (United States); Liren Zhu, Lihong V. Wang, California Institute of Technology (United States)
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Compressive temporal focusing microscopy
Paper 10505-4
Time: 9:40 AM - 10:00 AM
Author(s): Milad Alemohammad, Jaewook Shin, Jasper R. Stroud, Mark A. Foster, Johns Hopkins Univ. (United States)
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Coffee Break 10:00 AM - 10:30 AM
Session 2:
High-Throughput Imaging: Instrumentation and Analytics I
Monday 29 January 2018
10:30 AM - 12:00 PM
Location: Room 2018 (West Level 2)
Session Chair:
Mark A. Foster, Johns Hopkins Univ. (United States)
Multiplexing acquisition with spectral interleaving optical coherence tomography (Invited Paper)
Paper 10505-5
Time: 10:30 AM - 11:00 AM
Author(s): Audrey K. Bowden, Stanford Univ. (United States)
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A 100 Mfps image sensor for biological applications
Paper 10505-6
Time: 11:00 AM - 11:20 AM
Author(s): Takeharu Goji Etoh, Kazuhiro Shimonomura, Quang A. Nguyen, Ritsumeikan Univ. (Japan); Kosei Takehara, Kindai Univ. (Japan); Yoshinari Kamakura, Osaka Univ. (Japan); Paul Goetschalckx, Luc Haspeslagh, Piet De Moor, IMEC (Belgium); Vu Truong Son Dao, International Univ. (Viet Nam); Dzung H. Nguyen, Hanoi Univ. of Science and Technology (Viet Nam); Naoki Hayashi, Yo Mitsui, ASTRODESIGN, Inc. (Japan); Hideo Inumaru, CREF, Inc. (Japan)
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High-resolution multispectral imaging using a photodiode
Paper 10505-7
Time: 11:20 AM - 11:40 AM
Author(s): Liheng Bian, Jinli Suo, Feng Chen, Qionghai Dai, Tsinghua Univ. (China)
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Video-rate confocal phase imaging by use of scan-less dual comb microscopy
Paper 10505-8
Time: 11:40 AM - 12:00 PM
Author(s): Takahiko Mizuno, Eiji Hase, Takeo Minamikawa, Tokushima Univ. (Japan); Hirotsugu Yamamoto, Utsunomiya Univ. (Japan); Takeshi Yasui, Tokushima Univ. (Japan)
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Lunch Break 12:00 PM - 1:30 PM
Session 3:
High-Throughput Imaging: Instrumentation and Analytics II
Monday 29 January 2018
1:30 PM - 3:00 PM
Location: Room 2018 (West Level 2)
Session Chair:
Bennett L. Ibey, Air Force Research Lab. (United States)
Development and application of high-speed super-resolution and single-molecule imaging for cell biology studies (Invited Paper)
Paper 10505-9
Time: 1:30 PM - 2:00 PM
Author(s): Yasushi Okada, RIKEN Quantitative Biology Ctr. (Japan)
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High-speed particle tracking in microscopy using SPAD image sensors
Paper 10505-10
Time: 2:00 PM - 2:20 PM
Author(s): Istvan Gyongy, The Univ. of Edinburgh (United Kingdom); Amy Davies, Heriot-Watt Univ. (United Kingdom); Neale A. W. Dutton, STMicroelectronics (R&D) Ltd. (United Kingdom); Colin Rickman, Rory Duncan, Heriot-Watt Univ. (United Kingdom); Robert Henderson, The Univ. of Edinburgh (United Kingdom); Paul Dalgarno, Heriot-Watt Univ. (United Kingdom)
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Machine-learning-assisted optofluidic time-stretch microscopy for drug discovery and medical diagnostics
Paper 10505-11
Time: 2:20 PM - 2:40 PM
Author(s): Cheng Lei, Hirofumi Kobayashi, Yiyue Jiang, The Univ. of Tokyo (Japan); Yi Wu, Carnegie Mellon Univ. (United States); Baoshan Guo, Atsushi Yasumoto, Takuro Ito, Yutaka Yatomi, Yasuyuki Ozeki, Keisuke Goda, The Univ. of Tokyo (Japan)
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Label-free multi-class classification of phytoplankton based on quantitative phase time-stretch imaging
Paper 10505-19
Time: 2:40 PM - 3:00 PM
Author(s): Queenie Tsz Kwan K. Lai, Kelvin C. M. Lee, Kenneth K. Y. Wong, Kevin K. Tsia, The Univ. of Hong Kong (Hong Kong, China)
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Coffee Break 3:00 PM - 3:30 PM
Session 4:
High-Throughput Imaging: Instrumentation and Analytics III
Monday 29 January 2018
3:30 PM - 5:30 PM
Location: Room 2018 (West Level 2)
Session Chair:
Edmund Y. Lam, The Univ. of Hong Kong (Hong Kong, China)
Pushing the envelope in biological imaging with dual-view light sheet fluorescence microscopy (Invited Paper)
Paper 10505-13
Time: 3:30 PM - 4:00 PM
Author(s): Yicong Wu, Evan Ardiel, Hari Shroff, Ryan Christensen, National Institute of Biomedical Imaging and Bioengineering (United States)
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Light sheet microscopy revolutionizes dynamic multi-dimensional light microscopy of three-dimensional specimens (Invited Paper)
Paper 10505-14
Time: 4:00 PM - 4:30 PM
Author(s): Ernst Hans Karl Stelzer, Johann Wolfgang Goethe-Univ. Frankfurt am Main (Germany)
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High-throughput fluorescence imaging flow cytometry with light-sheet excitation and machine learning
Paper 10505-15
Time: 4:30 PM - 4:50 PM
Author(s): Hideharu Mikami, Taichi Miura, Yasuyuki Ozeki, The Univ. of Tokyo (Japan); Keisuke Goda, The Univ. of Tokyo (Japan), Univ. of California, Los Angeles (United States), Japan Science and Technology Agency (Japan)
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Adapting high speed and nonlinear optical systems to measure rapid changes in plasma membrane structure and potential
Paper 10505-16
Time: 4:50 PM - 5:10 PM
Author(s): Bennett L. Ibey, Joel Bixler, Caleb C. Roth, Hope T. Beier, Air Force Research Lab. (United States)
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Multi-channel imaging cytometry with a single detector
Paper 10505-17
Time: 5:10 PM - 5:30 PM
Author(s): Sarah Locknar, John Barton, Omega Optical, Inc. (United States); Mark Entwistle, Princeton Lightwave, Inc. (United States); Gary Carver, Robert Johnson, Omega Optical, Inc. (United States)
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Session PMon:
Posters-Monday
Monday 29 January 2018
5:30 PM - 7:30 PM
Location: Moscone West Level 2 & 3

Conference attendees are invited to attend the BiOS poster session on Monday evening. Come view the posters, enjoy light refreshments, ask questions, and network with colleagues in your field. Authors of poster papers will be present to answer questions concerning their papers. Attendees are required to wear their conference registration badges to the poster sessions. Poster authors, view poster presentation guidelines and set-up instructions at http://spie.org/PWPosterGuidelines.
Dual-comb single-pixel imaging in both amplitude and phase
Paper 10505-34
Time: 5:30 PM - 7:30 PM
Author(s): Kyuki Shibuya, Takeo Minamikawa, Tokushima Univ. (Japan), ERATO MINOSHIMA Intelligent Optical Synthesizer, Japan Science Engineering Co., Ltd. (Japan); Yasuhiro Mizutani, Osaka Univ. (Japan), ERATO MINOSHIMA Intelligent Optical Synthesizer, Japan Science Engineering Co., Ltd. (Japan); Hirotsugu Yamamoto, Utsunomiya Univ. (Japan), ERATO MINOSHIMA Intelligent Optical Synthesizer, Japan Science Engineering Co., Ltd. (Japan); Takeshi Yasui, Tetsuo Iwata, Tokushima Univ. (Japan), ERATO MINOSHIMA Intelligent Optical Synthesizer, Japan Science Engineering Co., Ltd. (Japan)
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Hybrid adaptive optics for high-throughput volumetric optical coherence microscopy
Paper 10505-35
Time: 5:30 PM - 7:30 PM
Author(s): Siyang Liu, Jeffrey A. Mulligan, Steven G. Adie, Cornell Univ. (United States)
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End-to-end learning for digital hologram reconstruction
Paper 10505-36
Time: 5:30 PM - 7:30 PM
Author(s): Zhimin Xu, SharpSight Ltd. (Hong Kong, China); Si Zuo, Aalto Univ. (Finland); Edmund Y. Lam, The Univ. of Hong Kong (Hong Kong, China)
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Direct digitizer to GPU DMA transfer for high speed customizable OCT processing
Paper 10505-37
Time: 5:30 PM - 7:30 PM
Author(s): Romain Deterre, Étienne De Montigny, Muneeb Khalid, Alazar Technologies, Inc. (Canada)
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A two-stage framework for DIC image denoising and Gabor based GLCM feature extraction for pre-cancer diagnosis
Paper 10505-38
Time: 5:30 PM - 7:30 PM
Author(s): Sawon Pratiher, Indian Institute of Technology Kanpur (India); Sabyasachi Mukhopadhyay, Indian Institute of Science Education and Research Kolkata (India); Asima Pradhan, Indian Institute of Technology Kanpur (India); Nirmalya Ghosh, Prasanta K. Panigrahi, Indian Institute of Science Education and Research Kolkata (India)
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Plasma plume expansion dynamics in nanosecond Nd:YAG laserosteotome
Paper 10505-39
Time: 5:30 PM - 7:30 PM
Author(s): Hamed Abbasi, Georg Rauter, Univ. Basel (Switzerland); Raphael Guzman, Univ. Hospital Basel (Switzerland); Philippe C. Cattin, Azhar Zam, Univ. Basel (Switzerland)
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Application of a fast skyline computation algorithm for serendipitous searching problems
Paper 10505-40
Time: 5:30 PM - 7:30 PM
Author(s): Kenichi Koizumi, Kei Hiraki, Mary Inaba, The Univ. of Tokyo (Japan)
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Highly-sensitive and large-dynamic diffuse optical tomography system for breast tumor detection
Paper 10505-41
Time: 5:30 PM - 7:30 PM
Author(s): Wenwen Du, Limin Zhang, Guoyan Yin, Yanqi Zhang, Huijuan Zhao, Feng Gao, Tianjin Univ. (China)
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Retinal health assessment using capsule networks with dynamic routing
Paper 10505-42
Time: 5:30 PM - 7:30 PM
Author(s): Henry Leopold, Vasudevan Lakshminarayanan, John Zelek, Univ. of Waterloo (Canada)
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Stochastic HKMDHE: An multi-objective contrast enhancement algorithm
Paper 10505-43
Time: 5:30 PM - 7:30 PM
Author(s): Sawon Pratiher, Indian Institute of Technology Kanpur (India); Sabyasachi Mukhopadhyay, Indian Institute of Science Education and Research Kolkata (India); Srideep Maity, Indian Institute of Engineering Science and Technology, Shibpur (India); Prasanta K. Panigrahi, Indian Institute of Science Education and Research Kolkata (India)
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Evaluation of a high framerate multi-exposure laser speckle contrast imaging setup
Paper 10505-44
Time: 5:30 PM - 7:30 PM
Author(s): Martin Hultman, Linköping Univ. (Sweden); Ingemar Fredriksson, Linköping Univ. (Sweden), Perimed AB (Sweden); Marcus Larsson, Tomas Strömberg, Linköping Univ. (Sweden)
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Tuesday 30 January Show All Abstracts
Session 5:
High-throughput Imaging: Applications
Tuesday 30 January 2018
8:30 AM - 10:00 AM
Location: Room 2018 (West Level 2)
Session Chair:
Liang Gao, Univ. of Illinois at Urbana-Champaign (United States)
Fluorescence lifetime imaging for real-time augmented reality in cancer surgery (Invited Paper)
Paper 10505-18
Time: 8:30 AM - 9:00 AM
Author(s): Laura Marcu, Univ. of California, Davis (United States)
Show Abstract
Deep convolutional neural network for single-cell image analysis
Paper 10505-12
Time: 9:00 AM - 9:20 AM
Author(s): Edmund Y. Lam, Nan Meng, Hayden K. H. So, The Univ. of Hong Kong (Hong Kong, China)
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Accurate classification of microalgal cells by frequency-division-multiplexed confocal imaging flow cytometry
Paper 10505-20
Time: 9:20 AM - 9:40 AM
Author(s): Hideharu Mikami, Jeffrey Harmon, Yasuyuki Ozeki, The Univ. of Tokyo (Japan); Keisuke Goda, The Univ. of Tokyo (Japan), Univ. of California, Los Angeles (United States), Japan Science and Technology Agency (Japan)
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Label-free cell-cycle analysis by high-throughput quantitative phase time-stretch imaging flow cytometry
Paper 10505-21
Time: 9:40 AM - 10:00 AM
Author(s): Aaron Mok, Kelvin C. M. Lee, Kenneth K. Y. Wong, Kevin K. Tsia, The Univ. of Hong Kong (Hong Kong, China)
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Coffee Break 10:00 AM - 10:30 AM
Session 6:
High-speed Nonlinear Imaging I
Tuesday 30 January 2018
10:30 AM - 11:40 AM
Location: Room 2018 (West Level 2)
Session Chair:
Kotaro Hiramatsu, The Univ. of Tokyo (Japan)
Stimulated Raman scattering microscopy and spectroscopy with a rapidly scanning optical delay line (Invited Paper)
Paper 10505-22
Time: 10:30 AM - 11:00 AM
Author(s): Minbiao Ji, Fudan Univ. (China)
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Multicolor stimulated Raman imaging of live microalgal cells using fast wavelength-switched laser pulses
Paper 10505-23
Time: 11:00 AM - 11:20 AM
Author(s): Yuta Suzuki, Koya Kobayashi, Dinghuan Deng, Yoshifumi Wakisaka, Keisuke Goda, Yasuyuki Ozeki, The Univ. of Tokyo (Japan)
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In-line balanced detection stimulated Raman scattering microscopy from a compact fiber-format laser source
Paper 10505-24
Time: 11:20 AM - 11:40 AM
Author(s): Dario Polli, Francesco Crisafi, Vikas Kumar, Giulio Cerullo, Politecnico di Milano (Italy)
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Lunch/Exhibition Break 11:40 AM - 1:30 PM
Session 7:
High-speed Nonlinear Imaging II
Tuesday 30 January 2018
1:30 PM - 3:00 PM
Location: Room 2018 (West Level 2)
Session Chair:
Dario Polli, Politecnico di Milano (Italy)
Multimodal nonlinear optical microscopy imaging and Raman spectroscopy for label-free digital pathology (Invited Paper)
Paper 10505-25
Time: 1:30 PM - 2:00 PM
Author(s): Zhiwei Huang, National Univ. of Singapore (Singapore)
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High-speed broadband Fourier-transform CARS microscopy
Paper 10505-26
Time: 2:00 PM - 2:20 PM
Author(s): Kotaro Hiramatsu, Kinegawa Ryo, Kazuki Hashimoto, Venkata R. Badarla, Takuro Ideguchi, Keisuke Goda, The Univ. of Tokyo (Japan)
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High-speed nonlinear FACED microscopy with multiplexed time-gated photon counting
Paper 10505-27
Time: 2:20 PM - 2:40 PM
Author(s): Jianglai Wu, Queenie Tsz Kwan Lai, Wenwei Yan, Kenneth K. Y. Wong, Kevin K. Tsia, The Univ. of Hong Kong (Hong Kong, China)
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Acceleration of Raman imaging rate by multi-line illumination
Paper 10505-28
Time: 2:40 PM - 3:00 PM
Author(s): Kentaro Mochizuki, Shunsuke Maeda, Taeho Lee, Osaka Univ. (Japan); Nicholas I. Smith, Immunology Frontier Research Ctr., Osaka Univ. (Japan); Katsumasa Fujita, Osaka Univ. (Japan)
Show Abstract
Coffee Break 3:00 PM - 3:30 PM
Session 8:
High-throughput In Vivo Imaging
Tuesday 30 January 2018
3:30 PM - 5:30 PM
Location: Room 2018 (West Level 2)
Session Chair:
Cheng Lei, The Univ. of Tokyo (Japan)
4K/8K CMOS-based, broad-view, high-resolution, and ultra-rapid in vivo imaging analysis (Invited Paper)
Paper 10505-29
Time: 3:30 PM - 4:00 PM
Author(s): Satoshi Nishimura, The Ctr. for Molecular Medicine, Jichi Medical Univ. (Japan)
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High throughput 3D microscopy for in vivo fluorescence imaging (Invited Paper)
Paper 10505-30
Time: 4:00 PM - 4:30 PM
Author(s): Meng Cui, Purdue Univ. (United States)
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Highly integrated label-free multiphoton nonlinear optical microspectroscopy imaging system for biomolecular imaging
Paper 10505-31
Time: 4:30 PM - 4:50 PM
Author(s): Jang Hyuk Lee, Jose Rico-Jimenez, Univ. of Illinois (United States); Aneesh Alex, GlaxoSmithKline (United States); Eric J. Chaney, Ronit Barkalifa, Haohua Tu, Marina Marjanovic, Univ. of Illinois (United States); Zane A. Arp, GlaxoSmithKline (United States); Stephen A. Boppart, Univ. of Illinois (United States)
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Video-rate hyperspectral two-photon fluorescence microscopy for in vivo imaging
Paper 10505-32
Time: 4:50 PM - 5:10 PM
Author(s): Fengyuan Deng, Changqin Ding, Jerald C. Martin, Nicole M. Scarborough, Zhengtian Song, Gregory S. Eakins, Garth J. Simpson, Purdue Univ. (United States)
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Two dimensional microcirculation mapping with real time spatial frequency domain imaging
Paper 10505-33
Time: 5:10 PM - 5:30 PM
Author(s): Xinlin Chen, Weihao Lin, Bixin Zeng, Wenzhou Medical Univ. (China); Min Xu, Fairfield Univ. (United States); XiuWei Zhu, Wenzhou Medical Univ. (China)
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