Disney's Coronado Springs Resort
Lake Buena Vista (Orlando Area), Florida, United States
9 - 14 February 2013
Course (SC1065)
Exploring Brain Connectivity in-vivo: from Theory to Practice
Saturday 9 February 2013
1:30 PM - 5:30 PM

Member Price Price Unavailable.
Non-Member Price Price Unavailable.
Student Member Price Price Unavailable.
  • Course Level:
  • Introductory
  • CEU:
  • 0.35
The development of Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) has opened up the possibility of studying the complex organization of the brain's white matter in-vivo. By measuring the diffusion of water molecules in tissues, the technique gives insights into the structure and orientation of major white matter pathways, and DT-MRI findings have the potential to play a critical role in the extraction of meaningful information for diagnosis, prognosis and following of treatment response. The course will guide participants through the fundamental aspects of DT-MRI data analysis, as well as the challenges of transferring cutting-edge DT-MRI techniques to clinical routine. The format will include a series of hands-on sessions with the participants running DT-MRI analysis on their own laptops, to provide a practical experience of extracting useful clinical information from Diffusion MR images. Participants will be guided through an integrated workflow for exploring the brain white matter in a series of datasets that will be provided as part of the course. The hands-on sessions will use DT-MRI tools from the NA-MIC toolkit, which include the 3DSlicer software, an open-source platform for medical image processing and 3D visualization used in biomedical and clinical research. This event is part of the on-going effort of the NIH-funded National Alliance for Medical Image Computing (NA-MIC) to transfer the latest advances in biomedical image analysis to the scientific and clinical community. This course is intended as a companion to SC1063, Diffusion Imaging. Attendees will benefit maximally by attending both courses.
Learning Outcomes
  • identify the different components of a DT-MRI fiber tract analysis pipeline
  • perform DWI/DTI data quality control
  • visualize 3D tensor fields and diffusion-derived maps
  • generate 3D reconstructions of white matter tracts in a normal subject and pathological case
  • extract and visualize DTI fiber tract profiles
  • identify the current challenges inherent in using DT-MRI data in the clinics
The course is designed for scientists, engineers, and clinical researchers who are interested in learning how to use Diffusion Tensor MR Imaging for mapping the white matter of the human brain in health and disease. This course does not need any prior knowledge, but it can ideally be combined with the course SC1063: Diffusion Imaging.
All attendees will need to bring a laptop to the course in order to run the demos. This course is intended as a companion to SC1063, Diffusion Imaging. Attendees will benefit maximally by attending both courses.
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