PicoQuant is a leading research and development company which was founded in 1996. The product portfolio encompasses ps pulsed diode lasers, ultra fast time taggers and photon counters, single photon sensitive detectors, time-resolved confocal and super-resolution fluorescence microscopes, and fluorescence lifetime spectrometers. More than 125 people currently work for the PicoQuant group, primarily in its German headquarters, and with strong sales and support teams in the USA and in China.
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PicoQuant Photonics North America, Inc.
9 Trinity Dr
West Springfield, MA
United States
01089-1825
Website:
www.picoquant.com
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PicoQuant Photonics North America, Inc.: Using rapidFLIMHiRes to visualize dynamic processes with ultra fast FLIM imaging and outstanding time resolution
PicoQuant's rapidFLIMHiRes approach redefines Fluorescence Lifetime Imaging (FLIM) by combining fast data acquisition with n outstanding time resolution. This method is the ideal tool for ultra fast FLIM acquisiton with up to several frames per second and reliable, quantitative analysis for a broad range of applications such as: imaging of dynamic processes (e.g., protein interaction, chemical reaction, or ion flux), highly mobile species (e.g., mobility of cell organelles or particles, cell migration), high throughput FLIM screening, and investigating FRET dynamics. Recent hardware and software improvements allow for increased data acquisition speeds without sacrifices in lifetime resolution. rapidFLIMHiRes is available for PicoQuants's LSM Upgrade Kits and as a special configuration for the time-resolved fluorescence micrsocope MicroTime 200.
Author(s): Maria Loidolt-Krüger, Fabian Jolmes, Matthias Patting, Michael Wahl, Evangelos Sismakis, André Devaux, Uwe Ortmann, Felix Koberling, Rainer Erdmann, PicoQuant GmbH (Germany)
Digital Forum: On-demand now
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Fluorescence Lifetime Imaging (FLIM) is an essential tool in Life Sciences, but up to now users had to chose between high timing precision or fast data acquisition when using Time-Correlated Single Photon Counting (TCSPC) electronics. Our approach, named rapidFLIMHiRes, allows recording several FLIM images per second with a temporal resolution of 10 ps. The method combines advances in fast scanning, hybrid photomultiplier detectors, TCSPC modules, and correction algorithms to reduce decay curve distortions. Thus fast processes can be observed with the high optical and temporal resolution achievable in confocal microscopy at a rate of several frames per second.
Author(s): Maria Loidolt-Krüger, Fabian Jolmes, Matthias Patting, Michael Wahl, Evangelos Sismakis, André Devaux, Uwe Ortmann, Felix Koberling, Rainer Erdmann, PicoQuant GmbH (Germany)
Digital Forum: On-demand now
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Fluorescence Lifetime Imaging (FLIM) is an essential tool in Life Sciences, but up to now users had to chose between high timing precision or fast data acquisition when using Time-Correlated Single Photon Counting (TCSPC) electronics. Our approach, named rapidFLIMHiRes, allows recording several FLIM images per second with a temporal resolution of 10 ps. The method combines advances in fast scanning, hybrid photomultiplier detectors, TCSPC modules, and correction algorithms to reduce decay curve distortions. Thus fast processes can be observed with the high optical and temporal resolution achievable in confocal microscopy at a rate of several frames per second.
Author(s): Christian Oelsner, Eugeny Ermilov, Volker Buschmann, Frank Birke, Matthias Patting, Uwe Ortmann, Rainer Erdmann, PicoQuant GmbH (Germany)
Digital Forum: On-demand now
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We will demonstrate the performance of a spectrometer-microscope assembly for characterization and analysis of samples in terms of lifetime, spectral and spatial resolution. This combined approach provides access to further information, which are not available when using only lifetime or steady-state experiments. The combination of both techniques in one setup can help to understand biochemical or physical processes by detecting changes in local environment such as pH, temperature, or ion concentration, and to identify molecular interactions or conformation changes via Förster Resonance Energy Transfer (FRET).
Exclusive offers and giveaways for SPIE attendees
Announcements
05 March 2021
Picture contest for young researchers
Three young researchers (< 35 years) will have their SPIE attendance fees refunded by PicoQuant. To enter the contest, send a selfie with your PicoQuant product along with your contact details, and a short description (~100 words) of what you are currently working on to events@picoquant.com until March 8, 2021.The lucky winners will be announced on March 10, 2021.
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10 February 2021
PicoQuant hosts conference on "Single Molecule Spectroscopy and Superresolution Imaging"
Like every year, Rainer Erdmann, Managing Director of PicoQuant, Felix Koberling, Head of Development Microscopy, PicoQuant, and Ingo Gregor, University of Göttingen, Germany, host the BiOS session BO503 on Single Molecule Spectroscopy and Superresolution, featuring talks by upcoming and established scientists. Be sure to check out the many fascinating talks in this session.
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10 February 2021
rapidFLIM HiRes: Visualize dynamic processes with ultra fast FLIM imaging and outstanding time resolution
Our improved rapidFLIM HiRes approach enables ultra fast and quantitative fluorescence lifetime imaging without sacrifices in lifetime resolution. Learn more about how this improved imaging method helps in studying fast processes such as fast changes in environmental parameters or environmental changes in the +++ invited talk of Dr. Fabian Jolmes, Sales & Application Specialist Microscopy +++ in the SPIE digital library from March 6 to 11, 2021.
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05 March 2021
Live chat hours March 6-11
We are available to answer your questions in live chats March 6-11, 12 am (midnight) – 6 pm PST (Pacific Standard Time/San Francisco Time/UTC-8). +++ We are also online at our Photonics West marketplace: https://spie.org/ExhibitorDetail?ExpoID=2062&ExhibitorID=50276