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Detection and quantification of lipid membrane binding on silica micro-tube resonator sensor (Proceedings Paper)

Author(s): Tao Ling; Sheereen Majd; Michael Mayer; L. Jay Guo
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Single Molecule Spectroscopy and Imaging, Jörg Enderlein; Zygmunt K. Gryczynski; Rainer Erdmann, Editors, 68620B

Date: 21 February 2008

Paper Abstract

Silica micro-tube resonator is a very attractive biosensor platform for label-free detection of bio-molecules by combining high sensitivity and simple fluidic handling. We report the study of lipid membrane binding on micro-tube sensor that is probed by a prism coupling technique. Prism coupling to the micro-tube resonance modes allows thick micro-tube to be used and the selectivity of high-sensitivity modes. We were able to identify and probe a special resonance mode that has very high Electrical field
DOI: 10.1117/12.763091
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