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Biomedical Optics & Medical Imaging

Optical phantoms mimic properties of tissue


BioMimic optical phantoms from INO reproduce the characteristics of light propagation (400-900 nm) in living tissue.

Medical imaging instruments are calibrated using standards fabricated in a controlled way, called phantoms, in order to validate performance (e.g., spatial resolution in radiography). With the increasing use of new in vitro and in vivo optical imaging systems by researchers, pharmaceutical companies, and the clinical community, new standards must be developed for the visible/near-infrared portion of the electromagnetic spectrum.

INO developed expertise and fabrication processes for solid phantoms consisting of polymers, which ensure a long shelf life and outstanding reproducibility of optical properties. Depending on tissue simulation to performed, these fabrication processes enable INO to adjust absorption and scattering properties on a specific wavelength band.

Based on optical-quality polymers, the optical phantoms can simulate a wide variety of tissue types, and include phantom varieties with VIS-NIR absorbing dyes and TiO2 scatterers. Phantom preparation with a number of layers of differing properties is possible; for fluorescence applications, it is possible to embed fluorescent inclusions with different properties at precise positions in the phantom volume.