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Micro/Nano Lithography

Liquid lens creates tiny, flexible laser on biochip

Like tiny Jedi knights, tunable fluidic micro lenses can focus and direct light at will to count cells, evaluate molecules, or create on-chip optical tweezers, according to a team of Penn State engineers. They may also provide imaging in medical devices, eliminating the necessity and discomfort of moving the tip of a probe.

Conventional, fixed focal length lenses can focus light at only one distance. The entire lens must move to focus on an object or to change the direction of the light. Attempts at conventional tunable lenses have not been successful for lenses on the chip. Fluidic lenses, however, can change their focal length or direction in less than a second while remaining in the same place and can be fabricated on the chip during manufacture.

"We use water and a calcium chloride solution because they are readily available and safe and their optical properties have been well characterized," said Tony Jun Huang, James Henderson assistant professor of engineering science and mechanics. "There are lots of possibilities about what fluids we can use. Most solutions change their refractive indices if the concentration changes."

He notes that they could use a variety of solutions with water. There are also a number of commercially available "refractive index fluids" which could potentially provide better optical properties and make these Liquid-Gradient Refractive Index (L-GRIN) lenses work even better.

Huang, working with engineering science and mechanics graduate students Sz-Chin Steven Lin, Michael I. Lapsley, Jinjie Shi and Bala Krishna Juluri and bioengineering graduate student Xiaole Mao, who is the first author on the paper, reported their work in a recent issue of Lab on a Chip.

Press release