Fluorescence lifetime imaging microscopy and its biomedical applications, high spatial resolution retinal imaging using parallel OCT and autofluorescence, biomedical photonics.
Biography
Junle Qu, Ph.D., is an Associate Professor at Shenzhen University, China. He graduated from Xi'an Jiaotong University with a Bachelor of Engineering degree in Electronic Physics in 1988, and he received a Ph.D. degree in Physical Electronics from Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences in 1998. Dr. Qu was a postdoctoral fellow at School of Optometry of Indiana University from 2001 to 2003. His research interests have focused on the development of novel optical imaging modality for biomedicine and his research activities involve fluorescence lifetime imaging microscopy, two-photon excitation fluorescence microscopy, parallel optical coherence tomography and its applications in high resolution retinal imaging etc. Dr. Qu has published more than 40 papers. He holds two Chinese patents and one US patent. Dr. Qu is the member of International Society for Optical Engineering, Optical Society of America and Chinese Optical Society.
Lecture Title(s)
Temporally and Spectrally Resolved Sampling Imaging with a Specially Designed Streak Camera We present a novel sampling imaging technique capable of performing simultaneous 2-dimensional (2-D) measurements of the temporal and spectral emission characteristics of various light emission processes using a specially designed streak camera. A proof-of-principle experiment is performed with a homemade multifocal multiphoton fluorescence microscope. The system was calibrated with a Fabry-Perot (F-P) etalon and a standard fluorophore solution (rhodamine 6G in ethanol) and was shown to have temporal and spectral resolution of 6.5ps and 3nm respectively as well as high accuracy and reproducibility in lifetime and spectrum measurement. Temporally and spectrally resolved images of 4×4 foci on the sample can be obtained with a snapshot. With the capability of simultaneous 2-D sampling measurements of temporally and spectrally resolved information, this technique may ultimately find applications in laser-induced plasma diagnostics, multi-well imaging and spectrally resolved multifocal multiphoton fluorescence lifetime imaging.
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