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Biomedical Optics & Medical Imaging

Eva Sevick Hot Topics presentation: Lymphatic Flow Imaging

Presented at SPIE Photonics West 2012
8 February 2012, SPIE Newsroom. DOI: 10.1117/2.3201202.05

Eva SevikEva Sevick presents research on lymphatic flow for the development of drugs to treat lymphatic diseases in "Lymphatic Flow Imaging." The presentation includes the first-ever video of lymphatic flow in humans.

Imaging through several centimeters of tissue requires near-IR light for penetration depth. A system using a matching NIR fluorophore and night-vision technology was developed to create movies of lymph flow. A patient sample set was identified as predisposed to lymphangiogenesis and a gene sequencing study led to determining the gene associated with this condition.

Eva M. Sevick is Professor and Cullen Chair in Molecular Medicine at the University of Texas Health Science Center's Institute of Molecular Medicine (IMM) where she currently directs the Center for Molecular Imaging.

She has pioneered the development of near-infrared fluorescence optical imaging and tomography for molecular imaging and currently has two clinical trials underway at the University of Texas Health Science Center and Memorial Hermann Hospital that employ the technology for novel diagnostic imaging of lymphatic function.