PerkinElmer, Inc. announces the launch of the Lamina multilabel slide scanner at the USCAP 2014 Annual Meeting. The Lamina scanner is a high throughput imaging system designed to help research pathologists to more easily study protein expression and the relationships between disease markers in formalin-fixed, paraffin-embedded (FFPE) tissue sections. This allows research pathologists to gain a deeper understanding of diseases for the development of more effective therapies and treatments.
Configured to meet the needs of a larger research facility, the Lamina scanner includes high-speed brightfield and fluorescence imaging modalities along with PerkinElmer's proprietary Autofluorescence Reduction Technology (ARTTM).
It is designed to reduce interference from autofluorescence -- an unwanted by-product of tissue fixation -- and fluorophore cross-talk, in which the signal from one fluorophore bleeds into multiple channels. Both of these effects obscure real signals, which can result in an incorrect assessment of a slide. The Lamina scanner delivers these improvements in real-time during whole-slide scanning, enabling clearer visualization of protein biomarker expression in fluorescently labeled tissues. As a result, the Lamina scanner allows users to obtain more accurate information from histological specimens.
The Lamina scanner produces exceptional-quality, digital, whole-slide images of hematoxylin and eosin, (H&E) immunohistochemistry (IHC) and immunofluorescence-labeled tissue sections and tissue microarrays (TMAs), which can be stored and shared electronically without degradation.