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SPIE Photonics West
30-January - 01-February 2018
San Francisco, CA, United States

MIRPHAB

Address
MIRPHAB
17 Rue Hamelin
Paris
France
75016
Company Description
Featured Product: Mid-Infrared Chemical Sensors

MIRPHAB is an all-services Pilot Line for the fabrication of Mid-Infrared sensors, a single access point to the best technology, facilities and expertise provided by a consortium of leading companies in the field of photonics. MIRPHAB provides services for device design and fabrication from chip processing on wafer level to packaging and testing. MIRPHAB reduces the barriers to introduce your chemical sensor into the market by granting your proposal up 230k€. www.mirphab.eu.
Announcements
16 November 2017
Europe Joins Forces Towards Commercialization of Novel Mid-Infrared Photonic Sensors
Mirphab – Mid-Infrared Photonics Devices Fabrication for Chemical Sensing and Spectroscopic Applications – is an
EC funded project granted with € 13m in a public-private partnership with Photonics21, with the goal of creating a commercially viable pilot line for the fabrication of mid-infrared sensors that is ready for business by 2020. Mirphab has launched its first open call.

http://onlinelibrary.wiley.com/doi/10.1002/opph.201690068/abstract
16 November 2017
Continuous Monitoring Of Chemicals In The Pharmaceutical Industry
Chemicals are widely employed across a range of industrial sectors allowing the manufacturing of many of the products that we use daily. From an apple to a car, chemicals can be employed at multiple points the production supply chain. However, their uncontrolled use can risk serious contamination of the environment, food production chain, and healthcare services.

For this reason, the pharmaceutical industry is heavily controlled to ensure the composition of drugs administered to patients. Related chemical processes require strict quality checks to assess the purity, reproducibility, homogeneity, and warn of the presence of contaminants, among other factors. Current evaluation techniques include sampling, transportation to a specialized laboratory, purification of the sample (which is done by skilled personnel), and the final detection using bulky and expensive equipment. Since these actions are time-consuming and costly, and usually the sample is destroyed during the analysis, only a small fraction of the final drug can be analysed. In addition, these analytical tools are bulky and requires optimization and calibration steps, which creates a hurdle for in-line monitoring.

In many cases, batch pharmaceutical manufacturing (where all the materials are charged before the start of processing and discharged at the end of processing) is now replaced by cleaner, flexible and more efficient continuous manufacturing, which can avoid off-line delays. In a continuous manufacturing process, material is simultaneously charged and discharged from the process.

Continuous manufacturing has some advantages when comparing with batch manufacturing such as no manual handling is required, increased safety, shorter processing times, more flexible operation and smaller ecological footprint. However, how to warranty that the product has a uniform content and quality within specified limits? Clearly, the answer is related to the implementation of in-line monitoring detection tools in the manufacturing process.

Mid-Infrared (Mid-IR) technology is based on the strong interaction of light with molecular vibrations. Spectroscopic sensing in the Mid-IR wavelength band (3-12 µm) is a powerful analytical tool since the chemicals exhibit their fingerprint region, intense adsorptions that allow unambiguous identifications and quantifications of molecules.

A Mid-IR sensor consists of: i) a laser source, usually Interband Cascade Lasers (ICLs) and Quantum Cascade Lasers (QCL), ii) the passive components (PICs) or free-optics, and iii) a detector (type-II InAs/GaSb superlattice (T2SL), InAsSb and Quantum Cascade Detectors (QCD)). Packaging of the final devices includes the integration of the photonics components and the electronics on the same platform which reduce the size of the sensing system (see image below). Other advantages are a high sensitivity and selectivity, which allows unattended, direct and fast detection of the sample without the requirement of any pretreatment - fundamental requisites to integrate these devices into manufacturing lines.

https://picmagazine.net/article/102598/Continuous_monitoring_of_chemicals_in_the_pharmaceutical_industry%C2%A0/feature
16 November 2017
Biophotonics revolution in Healthcare
More stringent environmental regulations, exhaustive control of the quality of food, and less-invasive medical diagnostics devices are social challenges that must be addressed in the next years. To face them, the development of new detection tools allowing cost-effective, fast and simple analysis is required. Sensors based on Photonic Integrated Circuits (PICs) are perfect candidates for these types of detection tools. However, there is an important lack of infrastructures and equipment to produce small series of pre-commercial PIC based sensors. To address these deficiencies, the Photonics Public Private Partnership (PPP) has launched MIRPHAB (Mid-Infrared Photonics Devices Fabrication for chemical sensing and Spectroscopic Applications) dedicated to the fabrication of chemical sensing devices and PIXAPP (Photonic Integrated Circuits Assembly & Packaging Pilot Line) with the aim of overcoming the assembly and packaging bottleneck which blocks the commercialisation of these detection systems.
http://onlinelibrary.wiley.com/doi/10.1002/opph.201770306/epdf
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