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Principles and Applications of Optical Coherence Tomography (SC312)

Course Level: Advanced
Instructor: James G. Fujimoto, Massachusetts Institute of Technology (United States)

Course Details

Optical coherence tomography (OCT) is a new imaging modality, which is the optical analog of ultrasound. OCT can perform high resolution cross sectional imaging of the internal structure of biological tissues and materials. OCT is promising for biomedical imaging because it functions as a type of optical biopsy, enabling tissue pathology to be imaged in suit and in real time. This technology also has numerous applications in other fields ranging from nondestructive evaluation of materials to optical data storage. This course describes OCT and the integrated disciplines including fiber optics, interferometry, high-speed optical detection, biomedical imaging, in vitro and in vivo studies, and clinical medicine

Learning Outcomes

This course will enable you to:

  • describe the principles of optical coherence tomography (OCT)
  • explain a systems viewpoint of OCT technology
  • describe OCT detection approaches and factors governing performance
  • describe ultrafast laser technology and other low coherence light sources
  • describe OCT imaging devices such as microscopes, hand held probes and catheters
  • describe functional imaging such as Doppler and spectroscopic OCT
  • provide an overview of clinical imaging including clinical ophthalmology, surgical guidance, and detection of neoplasia and guiding biopsy
  • gain an overview of materials applications
  • discuss transitioning technology from the laboratory to the clinic
Intended Audience

This material is appropriate for scientists, engineers, and clinicians who are performing research in medical imaging.


James G. Fujimoto is Professor of Electrical Engineering and Computer Science at the Massachusetts Institute of Technology. His research interests include femtosecond optics and biomedical imaging and his group is responsible for the invention and development of optical coherence tomography. Dr. Fujimoto is a member of the National Academy of Sciences and National Academy of Engineering. He is co-chair of the SPIE BIOS symposium and co-chair of the conference on Optical Coherence Tomography and Coherence Domain Techniques at BIOS. Dr. Fujimoto is a co-founder of LightLabs Imaging, a company developing OCT for intravascular imaging that was recently acquired by St. Jude Medical.


Attendee testimonial:
Great course from the inventor! What more can you ask for.[/l]

Continuing Education Units

IACET Authorzed Provider
As an IACET Accredited Provider, SPIE offers CEUs for its programs that qualify under the ANSI/IACET Continuing Education Standard.