The objective of radiation treatment of cancer is eradication of the tumor. The disadvantage of radiation therapy is that it may injure or destroy adjacent normal tissues. Therefore, if we could focalize the radiant energy exactly on the tumor cells, then the adjacent normal tissues would be protected. X-ray holography permits us the realization of this idea. In this paper three methods are proposed in order to record and reconstruct required holograms by x-ray and the advantages and disadvantages of each method are discussed.

Thin films of biocompatible ceramic were fabricated by pulsed laser deposition on cylindrical implants. Diamond- like carbon films were deposited in vacuum on titanium alloy prostheses, heated to 90 degrees C. Coated prostheses were implanted into legs of rats and osseointegration higher than 60 percent was determined. Thin films of hydroxyapatite were created on real dental implants at 500 degrees C in Ar-water vapor atmosphere. Coated implants were implanted into mandibula of minipigs to study load free osseointegration. Results and experiences are presented and discussed.

Erbium lasers deliver laser radiation near 3 micrometers and are a promising alternative to excimer laser photorefractive keratectomy (UV-PRK). In addition to easier handling due to all solid state technology, especially when operated in the fundamental mode, IR-PRK eliminates the potential of mutagenic side effects associated with UV-PRK. However, a successful IR-PRK for the clinic treatment in the near future demands both technological development of erbium lasers in different operation modes and clinical investigation of interaction between 3 micrometers radiation and human corneas. The excellent cooperation between university, company and hospital makes this possible. Uncoated thin plates made from infrared materials were found to be effective etalon reflectors with high damage threshold as high as 1 GW/cm² for erbium lasers. Four kinds of such reflectors were successfully tested in Q-switched Er:YAG-laser at 2.94 micrometers and Er:Cr:YSGG-laser at 2.80 micrometers. Very stable operation of our erbium lasers with high output energy both in free-running and Q-switched modes is realized. First infrared photorefractive keratectomy (IR-PRK) for myopic correction in human corneas by a free-running erbium laser based on our new construction concepts was achieved.

Precancer and background diseases of the oral mucosa and lips, such as lichen planus, chronic ulcers and fissures, meteorological heilit, lupus erythematosus, after radiation heilit were treated by low-intensity laser irradiation. Laser therapy of the over-mentioned diseases was combined with medicinal treatment. All the patients were selected and treated in the limits of dispensary system. THe choice of diagnostic methods were made according to each concrete nosological form. A great attention was paid to the goal- directly sanitation of the oral cavity and treatment of attended internal diseases. The etiological factors were revealed and statistically analyzed. The results received during our researches demonstrated high effectiveness of laser irradiation combined with medicinal therapy in the treatment of oral mucosa and lips precancer diseases.

The complication of a laser induced tube fire during surgery was first published in 1979. The protection of tracheal tubes against ignition is necessary to enable a safe laser surgery of the upper airway. in an experimental study a new compound tube was tested: this tube had a higher laser resistance than a pure metal tube. The damage threshold of this tube was tested against the emission of various lasers as CO₂. The metal tube was damaged within seconds at CO₂ laser power densities of 10³ W/cm² whereas the damage threshold of the compound tube was 3.10⁶ W/cm². We compared the compound laser tube to the so far used metal tube in a prospective clinical trial in our department of ENT in patients undergoing CO₂-laser surgery of the upper airway. 66 patients were included into the study: 33 received the compound tube, 33 the metal tube. During endotracheal intubation the handling of the compound tube was better. During laser surgery high airway pressures occured more often with the metal tube. Whereas kinking was the problem of the compound tubes. Destruction of cuffs occured in both groups but did not cause any complications. No tube or cuff fire was noticed.

The analysis of the results of three laser methods of skin cancer treatment in 1535 patients has been made. In 112 patients laser dissection (LD), in 1341 patients laser photodestruction (LPD) and in 82 patients photodynamic therapy (PDT) was performed. LPD was performed in patients with tumors 1.0 to 1.5 cm and with superficial tumors of body and extremities up to 5.0 cm diameter. LAser wounds healed under the crust. Tumor recurrence in 2.5 to 8 months was found out in 22 patients. LD was performed in patients with primary skin tumors 1.0 to 5.0 cm in diameter. The laser wound was sutured or enclosed with the transported skin flap. Tumor recurrence was found out in 3 patients. PDT was performed in patients with multiple, large, recurrent, residual tumors and in cases of 'inconvenient' localizations of tumors on the face. The treatment had effect in 100 percent of tumors. Our experience in use of different laser techniques for skin cancer treatment shows that each of these methods has its own indications and application areas. They are not competitive with each other. These techniques widen the abilities of modern oncology in skin cancer treatment.

Photo dynamic therapy (PDT) with use of two Russian photosensitizers, photohem (hematoporphyrine derivative) in the dosage 1.5-5.0 mg/kg of body weight and photosense in the dosage 0.5-1.5 mg/kg of body weight has been provided in 26 patients with spread recurrent tumors of oral cavity. During PDT power density has been from 50 to 1000 mW/cm². Light irradiation doses ranging from 50 to 600 J/cm². Therapeutic effect in term from 2 months to 3 years took place in 24 patients. In 18 cases complete resorption of tumor was achieved, in 6 cases, partial resorption. No effect was found in 2 cases. Our experience supposes that PDT appears to be a reasonable alternative to the traditional therapy of recurrent tumors of oral cavity.

Transmyocardial laser revascularization (TMR) for the treatment of medically unresponsive angina pectoris has been shown to be clinically effective. The mechanism of its action, however, is not quite understood. Over the last five years my collaborators and I have conducted a variety of in vivo and in vitro studies using different animal models, lasers and experimental protocols. The results seem to indicate that the mechanism of action of TMR is related to neovascularization rather than chronically patent channels, as originally proposed.

The Nd:YAG laser has been marketed as an instrument for use on both hard and soft dental tissues. Its potential for use on hard tissues is limited but it may be the instrument of choice for use in certain soft tissue procedures. The aim of this study was to examine the effects of the Nd:YAG laser on amalgam restorations which frequently occur on tooth surfaces adjacent to areas of soft tissue which may be subjected to the laser. The amalgam used was Tytin. The laser firing was controlled by a computer and a constant repetition rate of 40 Hz was used. Energy per pulse was altered as follows, 30 mJ, 40 mJ, 60 mJ, 80 mJ, 120 mJ and 140 mJ. Exposure times of 0.05 sec, 0.125 sec, 0.25 sec, 0.5 sec, 1 sec, 2 sec, 3 sec, 4 sec, and 5 sec were used. The width of defect was measured using a Nikon measurescope with 10x magnification and it was established that the damage threshold lies between 0.125 sec and 0.25 sec for 30 mJ per pulse. The data was analyzed using a one way ANOVA statistical test. There was a significant correlation between the width of the defect and energy per pulse setting as well as exposure time. The findings indicate that amalgam restorations are prone to damage from inadvertent laser exposure and clinicians must take measures to protect such restorations during lasing of soft tissues.

In this paper, the principles of light propagation in tissue and techniques for measuring the optical parameters of tissues are briefly described. A new approach to measure optical parameters has been developed. We combine the solution of the diffusion theory with a result of Monte Carlo simulation to calculate the optical parameters of several mammalian tissue. This indirect approach might be used to determine the optical properties of human tissue. In addition, we also believe that the refractive index of bio- tissue is another important optical parameter in tissue optics. Recently, we have developed a new simple method based on total-internal-reflection to measure the refractive index of tissue. The main advantages of the method are its elimination of multiscattering effects, suitability to a small sample, and excellent accuracy of measurement. The refractive indices of skin from people of different age, sex and skin color in vivo was recently measured. We believe that it is the first set of data of index of refraction of human tissue in vivo.

Thirty patients with advanced liver cancer were treated by interstitial photodynamic therapy (PDT). These included 28 hepatocellular carcinoma and two adenocarcinoma, 19 primary tumors and 11 recurred follow other treatments. The diameter of tumors were 7-10cm in 13 cases and 10-16cm in 17 cases. In this study, an argon laser pumped dye laser system was used to give a CW laser beam at 630 nm which was split and coupled into there optical fibers. The patients were injected intravenously with photosensitizer hematoporphyrin derivative at a dose of 5mg/kg body weight 48 hours before PDT. Then the fibers were inserted into tumor by ultrasound- guided percutaneous puncture. The inserted irradiation points were spaced in entire tumor with the light release power 300mW and the irradiation time 12 minutes per point. Total 52 treatments were performed in 30 patients. Among them, 14 cases were treated only one time and 16 cases via 2-3 times. The follow-up was carried out in 25 cases for 12- 24 months. The results show that significant remission was 22 percent in those patients by only one treatment and 62 percent in those via 2 to 3 treatments. The shrink rate of tumor size was over 90 percent in five of six cases after treatment 3. The survival time has been over one year in 12 cases. No obvious change to be found for all patients in liver function test, renal function test and blood routine examination. The level of AFP indicated a descending trend after PDT. This work indicate that PDT is effective and safe for the treatment of large liver cancers including those recurred follow hepatic resection and those failed in hepatic artery infusion embolic chemotherapy.

In this paper, we did integrated research of laser medicine and photonics from the viewpoint of system-specific time. After establishing system-specific time dependent Maxwell equations in vacuum and in medium, we derived the non-decay optical transmission condition. We then put forward the concept of biological units that interact with laser radiation directly, and discussed the coherent interaction of laser radiation with biological units in terms of identical particle model and system-specific time quantum theory. We also introduced time to represent processes, discuss the time-coupling relation of the interaction of laser radiation with biological units and the corresponding biological processes, and generated the biological information of photons of laser radiation.

Autofluorescence of the tumor and surrounding tissue is the largest background source in fluorescence diagnosis. A new system which applied computer image processing technique to lung cancer localization by laser fluorescence bronchoscopy has been developed to subtract the autofluorescence background. The results of our trial tests in tissue- simulating phantom and the porcine thigh muscle models are satisfied. There is great hope that this computer-assisted image processing system will significantly enhance the contrast of fluorescence image and drop false results for early human lung cancer examination.

Allergic rhinitis is a common disease. Although it is already treated well clinically by widely using a new technology laser that is very popular with patients, but it is still not found home and aboard the detail research report about the pathological changes of nasoturbinal tissues before and after laser treatment. Recently, in order to further study the histopathological changes of the oedematous nasoturbinal mucosa irradiated by Nd:YAG laser. We have made pathological observation of the biopsy.

The whole blood absorption spectrum of human beings and monkey, dog, sheep, rabbits, mouse, chicken are measured. The results show the blood absorption spectrum of the animals is very similar to that of human beings. This results is useful to the research on the laser irradiating blood therapy.

Since 1989, we have cured 367 persons of facial acne of different course by using direct irradiation of high-power CO₂ laser combing with operative therapy of low-power CO₂ laser. The cure rate is 100 percent. In this paper, we stated the therapeutic approach. It was shown that this therapeutic approach is simple and effective, and its recurrence rate is zero. There are no cicatrices after healing. It is easy to accept it, and is worthy of extension.

In this paper, we put forward the quasi-hormone model on laser biostimulation (QHML) and the quasi-peptide-hormone model on laser biostimulation (QPHML). QHML supposes the chromophore absorption in a cell allows the photon of low- energy laser irradiation to act as a carrier of bio- information as a hormone does. QPHML further supposes the chromophore absorption in the cell membrane couples with intracellular messenger through GTP-binding protein and mediates laser biostimulation as following: Hot color laser irradiation activates cAMP phosphodiesterase through G_i protein or activates phosphoinositide phospholipase C through G_q protein: cAMP$ARDN, cGMP $ARUP. COld-color laser irradiation activates adenylate cyclase through G_s protein; cAMP$ARUP, cGMP$ARDN. QPHML is verified by its successful applications at the cellular level, the clinic level, and the epidemiological level. In this paper, we also study light-cell interaction from time viewpoint. We define a time representing a process, and show the time parallel principle representing the time relationship of two weakly coupled processes. We then apply the time parallel principle to studying light-cell interaction mediated by the chromophore in the membrane, respectively, and provide theoretical foundation for QPHML.

The steady fluorescence spectra and fluorescence decay profiles from cancerous human lung tissues in vitro are measured using time-resolved technique. The fluorescence decays could be obtained by least-square fitting based on monoexponential function, with fluorescence lifetime constants of 6.3, 5.6 and 5.1 ns, respectively, corresponding to the normal, squamous carcinoma and adenocarcinoma tissues. The results show that they decay time of tumor tissue is a bit fast compared to the normal tissue.

Because of its high power and excellent optical features, laser has almost been applied to everywhere of medical research and clinic. Over the past several years, laser medical has achieved a rapid progress, and laser medical instruments has developed promptly, each new wavelength can be successfully applied in diagnostic and treatment of diseases. Among the medical lasers, Nd:YAG solid-state laser systems have proven useful in surgical use operate, such as neurosurgery, gastroenterology, cardioangiology, urology, gynecology, dermatology and ENT. As with other solid-state lasers, the Nd:YAG laser can be made to emit various wavelengths by means of suitable resonator configurations and some newest solid-state laser technology, pumped by the Krypton lamp, the Nd:YAG laser at room temperature exhibits transition at 1.06 micrometer Nd:YAG, using nonlinear crystal and Q-switch to double its frequency can attain 0.53 micrometer green beam. In our laser systems, the efficiency at 1.06 micrometer is more than 3 percent, an efficiency of 0.5 percent at 1.32 micrometer and 0.53 micrometer can be attained. For a power of 100w at 1.06 micrometer, 15w at 1.32 micrometer and 0.53 micrometer can therefore be produced. All of three kinds Nd:YAG laser hold these characteristics: high output power; optical fiber transition that can be cooperated with endoscope. The paper mainly discusses laser operating characteristics and clinic applications of three kinds wavelengths at 0.53 micrometer 1.06 micrometer and 1.32 micrometer Nd:YAG laser systems.

The concept of bio-speckle activity and its physical expression was proposed, and the sensibility of the activity to the mobility of red cells in blood capillary is studied clinically.

Fluorescence properties of stomach tissues have been investigated to determine whether malignant specimens can be discriminated in vitro. Differences between normal and tumor tissues are found that concern both the intensity distribution and spectral shape of the autofluorescence emission. According to the distinctions tumor tissues would be differed from the normal tissues. The resulting spectra could be differentiate histologically stomach abnormal tissues from normal tissues with a sensitivity and specificity value of 90 percent and 92 percent. Furthermore, fluorescence spectra from human stomach normal and malignant tissues have been measured in real time in vivo.

Biophoton emission (PE) method is a non-invasive way revealing biophysical interactions in living tissues. Since its mechanism is not very clear, its acceptance is limited. Gu has presented the quantum theory on biophoton emission according to the Dicke model. However, the Dicke model does not apply to biological system. In this paper, we studied PE by using the identical particle model, the interaction of identical particles by quantum chemistry, as well as the transition of the system interacting with radiation by the time quantum theory on radiation-matter interaction put forward by the first author and his cooperators. It was shown that the identical particles form coherent states, the photon emission probability of the superradiant state is a liner function of N and N², and the one of the subradiant state is zero. In other words, the photon emission intensity represents the coherent states of the identical particle system. The linear relationship of N and N² agrees with the PE experiment results on early drosophila embryos. The research on the cell division cycle showed that the superradiant states correspond to the late S phase. This is why PE can be used to differentiate human tumor tissues from normal ones. We also studied induced PE.

Using ultra-fast laser pulse for source, lots of research in measuring the transfer characteristics of linear optical system have been done. Because the sample ability and time resolution of the measurement system are limited, what we measure is not the temporal profile of single pulse but the overlapping profile of numerous pulses. So the time-resolved transfer function of linear optical system can't be obtained directly. But we have founded the model of it with the knowledge of statistical optics. With this model and measurable data, the time-resolved transfer function and impulse response of linear optical system for ultra-fast pulse could be obtained. Here, a grating spectrometer is used for the linear optical system and the source is Ar-ion laser pumping dye laser. The input and output data of the spectrometer have been measured when the wavelength changed from 590 nm to 630 nm with the step of 10 nm. Applying the model, we have obtained the time-resolved transfer function of grating spectrometer in different wavelength. The pulse broadening characteristics of grating spectrometer in different wavelengths is also discussed in this paper.

The peripheral vision display system (PVDS) presents the pilot with a gyro stabilized artificial horizon projected onto the instrument panel by means of a red laser light source. The pilot can detect changes to aircraft attitude without continuously referring back to his flight instruments. The PVDS effectively applies the peripheral vision of the pilot to overcome disorientation. This paper gives the principles of the PVDS, according to which, we have designed the PVDS and used it for aviation medicine.

Different methods of optical imaging of biological media based on time-resolved and low-coherence techniques are discussed, including the use of streak camera, Kerr gate, electronic holography and the low-coherence interferometry. The time-resolved techniques use ultrashort laser pulses and the photons traveling different paths can be detected selectively because they have different time of flight. The low-coherence techniques use light sources with broad spectrum and low coherence length to achieve high resolution.

The auto-fluorescence of breast cancer cells, early malignant cells of cystic mazoplisis and simple mazoplisis cells is researched with a confocal laser scanning microscope. It is found that there is a correlation between the cell malignant degree and its auto-fluorescence intensity: the auto-fluorescence in the plasma of breast cancer cells is most intensive, in the plasma of early malignant cells of cystic mazoplisis is less and there is no auto-fluorescence observed in the plasma of simple mazoplisis cells. This auto-fluorescence characteristic may provide an important basis for early diagnosis of tumor.

Much research has been made into low-powered He-Ne laser radiating treatment. Our He-Ne laser treating instrument can transmit double beams in two ways, which is quite different from the old-typed He-Ne laser instrument having one single beam in one way. The power of 250mm-laser totals 2.8mw-3. 5mw, nearing the theoretical value. The invention not only increases the laser radiating power, with convenient treatment of patients, but also eliminates the technical prejudice against radiating beams in one way. Since 1994, three two-way He-Ne laser instruments have been used in the clinical experiments on the ophthalmology in Dalian Railway Hospital. After concentrated treatment of the period of 3 winter and 3 summer vacations, 951 near-sighted eyes in 679 cases of near-sightedness of teenagers were treated. The recent total efficiency is 94.4 percent. The efficiency investigated after half a year is up to 60 percent.

The effect of He-Ne laser on the intracellular bactericidal and digestive function to C albicans of mice peritoneal M(theta) has been studied with the fluorescence microscope after acridine organge staining. The results indicated that the bactericidal and digestive function of M(theta) in irradiated groups, expressed more active than that in the non-irradiated group, and showed significant difference. The comparison between the different irradiated groups also showed marked difference. Ultrastructure changes of M(theta) were observed under the E/M and the content of a-Acetate Naphthy esterase in lysosome were measured by image analysis, the results demonstrated that M(theta) in the irradiated groups present marked change in ultrastructure and the GN, GA, GA/CA, IOD of esterase increased significantly. The results suggested that the He-Ne laser with appropriate dosage could activate M(theta) , and enhance anti-infection immunity.

In order to study the effect of He-Ne laser on peritoneal M(Phi) phagocytosis, and make into inquiry their mechanisms, in this paper, ShenQue acupoint of mice abdomen was irradiated by He-Ne laser at the dosage of 63.7J/cm² for 3, 5, 7 or 10 days respectively, 5 minutes each day. The results were as follows: 1) The phagocytosis and phagocytic index of M(Phi) of irradiated groups were higher than that of control group. 2) The GN, GA, GN/GA and IOD of non-specific esterase of M(Phi) of irradiated groups were obviously higher than these of the control group. 3) The M(Phi) of the irradiated groups presented more abundant and longer pseudopodia, contains more abundant lysosomes and phagosomes that of the control group. The results demonstrated that He- Ne laser with appropriate dosage can activate the macrophages and enhance organic immunity.

We report the effect of laser wavelengths and HpD on diffuse reflectance of tumor surface in mice. Three kinds of lasers of six different wavelengths and hemetoporphyrin derivative as photosensitizer were used in the experiment. Tumor- bearing mice were divided into two groups. The mice of one group were given an i.p. injection of HpD 10 mg/kg. 24 hours later, the laser diffuse reflectance of tumor surface of the mice of two groups were measured by a single integrating sphere system with laser in six wavelengths. The results of measurement showed that significant difference of diffuse reflectance on tumor surface between the visible laser light and infrared laser light were observed. There was no significant difference in diffuse reflectance on tumor surface with and without i.p. injection of HpD. So it is unnecessary to consider the effect of HpD when calculating the actual laser dose irradiated into the tumor. The diffuse reflectance of tumor surface reaches its maximum at 1060nm wavelength, as twice as at 514.5 nm wavelength. It is hence concluded that diffuse reflectance should be taken into consideration when calculating the actual laser density for irradiation on tumors.

The present paper reports the effect of hyperthermia (HT) induced by Nd:YAG laser and photodynamic therapy (PDT) by AR⁺ laser radiation in combination on the transplanted sarcoma 180 in CM mice. Tumor-bearing mice were divided into four groups: A) control group, B) HT group, C) PDT group and D) PDT followed by HT group. HT was induced by Nd:YAG laser radiation and the temperature at tumor edge was control at 43 degrees C for 30 minutes. Tumor-bearing mice of group C and D were given an i.p. injection of HpD 24 hours prior to AR⁺ laser radiation. The experiments show significant increases in inhibition rates against the S-180 in CM mice by the HT and PDT combination, compared to those by either HT or PDT alone. With that of Group D being the lowest, the DNA contents of tumor cells in the four groups are of statistical significance too. These results suggest the combination of HT induced by Nd:YAG and PDT by Ar⁺ laser radiation may become a new method of tumor treatment.

This article expounds objectively by full and accurate materials about 'ILLLIT' that takes the He-Ne laser as a representative in five sides: 1) the Chinese and ENglish name of 'ILLLIT'; 2) THe review of the history that 'ILLLIT' was introduced into our country; 3) The clinical effect and the basic research of 'ILLLIT'; 4) The comparison between 'ILLLIT' and 'UBI'; and 5) The questions facing 'ILLLIT' and prospects in our country. The inquiry that authors raise a view on base of his research and practice is expected, so as to clear up some confusion state and indistinct understanding about 'ILLLIT' in our country, and to make it as a clinical treatment of low-reaction-level laser that has a glorious future to take the healthy and developmental road.

In order to find a therapy which doesn't have any influence upon the patients working and living and also makes no pain to the patients, CO₂ laser is used to treat the 17 patients with subungual hematoma (SM). Satisfactory curative effect is obtained. Through the clinical observation on the treatment of the 17 cases with SM, the effective rate reached 98 percent. CO₂ laser is sure to provide safe, simple operation and short curative course with no pain to the patients, it has a certain practical value for clinical application.

Since 1989, 42 cases with low anal fistula were operated with laser and ordinary methods respectively. During the operation, secreted or charred tissues were extracted from the surface of the wound for bacteria culture. Experimental group (laser method): no bacteria were found in 24 cases operated by laser method. Control group (ordinary method): bacterial were found in 16 out of 18 cases operated by ordinary methods. The results of two different group showed that they had statistical difference for P < 0.001. So, CO₂ laser is proved to be a definitely practical tool in surgical use for its bacteria killing power. While the anal fistula were operated by the laser, the neurotic carboatomic tissue can block blood vessel and prevent infection from spreading. The high temperature produced by the carboatomic action have enough ability to kill directly the bacteria living in the anal fistula.

The activation for the natural water with 10.6 um CO₂ laser are investigated experimentally. When the water are irradiated by CO₂ laser beam, vibration of the water molecules is greatly strengthened, and form the water with short molecule chain structure: 'activated water'. The activating experimental process and results are reported. The most principal observation target of activated water is investigated by comparing activated water with ordinary water.

Based on the relationship between music and nature, the paper compares laser and light with music sound on the principles of synergetics, describes music physically and objectively, and proposes a music holographic therapy by laser. Maybe it will have certain effects on mechanism study and clinical practice of the music therapy.

When the low level He-Ne laser irradiation on both extracorporeally and intracorporeally circulatory blood, it has following useful stimulating functions for the living things: reduce the content of blood plasma middle-molecule substances, increase serum superoxide dismutase, improve hemorheological properties, raise immunity function of organism, etc. We developed the intravascular low level He- Ne irradiation therapeutic apparatus. A He-Ne laser beam of 632.8nm is coupled into 50/125 micrometers optical fiber with the aid of the free lens coupler, after that it entered into the laser pun through the fiber optic connector. The attenuate coefficient of the lens coupler can adjust continuously, so as to choose continuously the output power of the laser pin from 0 to 5 mW. In the pipe of the laser pin there is a large core fiber of 150/190 micrometers, they are stuck to each other. The diameter of the laser pin is less than 0.4 mm, thus it may get into infusion pin of 7, not used with intravenous casing pipe pin. Because it is adopted that the low priced fiber-optic connector, the laser pin can be used only once.

Objective: to investigate the effect of therapy to local infection using He-Ne laser. Method: we adopt He-Ne laser made in Harbin Laser Institution to irradiate directly infected gluteal surface areas. Result: all cases were cured. Conclusion: He-Ne laser is benefit for infected gluteal muscles.

The developments in tools based on information technology are assumed to have a fundamental impact on medicine. In conjunction with other changes in the management of health care, these developments lead to a breakdown of traditional boundaries between primary and new infrastructures in health care therefore evolved. Noninvasive patient monitor technology applied is aimed to encourage its employment for the benefit of more patients of is in need of health care on diagnosis and therapy procedures. Medical blood gases analysis mainly consists of three incidental parameters, that is, the partial pressure of oxygen and carbon dioxide and the negative logarithm of hydrogen ion activity. Since there are several sophisticated blood gas analyzers commercially available, the question arises whether there is still some reason to look for additional methods. Since it is known that optical sensors exist for measuring hydrogen ions and oxygen in blood gas analysis. We have tested laser optical fiber sensor indicators, which are more sensitive than absorption indicators. The values of blood samples determined by this meter and by ABL-30 blood gas analytic meter were well correlated, which shows that the slope/intercept values are very close and the correlation coefficients are greater than 0.97 for all the three parameters.

Results of a new noninvasive technique for pulp detection that is based on monitoring the time variations in the laser speckle pattern from a human tooth are presented. The paper also contains preliminary results of experiments and attempts at mathematical modeling of multiple scattering of a laser beam from a solid cylinder.