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Proceedings of SPIE Volume 2371

5th International Photodynamic Association Biennial Meeting
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Volume Details

Volume Number: 2371
Date Published: 1 March 1995
Softcover: 106 papers (630) pages
ISBN: 9780819417169

Table of Contents
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Clinically relevant technology in photodynamic therapy and photodynamic diagnosis
Author(s): Michael Unger
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Photodynamic therapy using 5-aminolevulinic acid-induced photosensitization: current clinical status
Author(s): Stuart L. Marcus; Allyn L. Golub; D. Geoffrey Shulman
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Studies on 5,10,15,20-tetrakis(m-hydroxyphenyl)chlorin, mTHPC (Temoporfin)
Author(s): Raymond Bonnett
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Influence of serum proteins on the accumulation of aminolaevulinic acid-induced protoporphyrin IX in cells in culture
Author(s): M. M. Weir; David I. Vernon; Stanley B. Brown
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Comparison of the influence of a water-soluble polymer carrier on the tumor localization and biodistribution of mesotetrametahydroxyphenylchlorin (mTHPC) in two animal models
Author(s): P. Westermann; Thomas M. Glanzmann; S. Folli; Daniel Braichotte; Martin Forrer; Snezana Andrejevic-Blant; J.-P. Mach; Philippe Monnier; Hubert van den Bergh
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Evaluation with mTHPC of early squamous cell carcinomas of the cheek pouch mucosa of Golden Syrian hamsters as a model for clinical PDT of early cancers in the upper aerodigestive tract, the esophag
Author(s): Thomas M. Glanzmann; Jean-Francois Theumann; Martin Forrer; Daniel Braichotte; Georges A. Wagnieres; Hubert van den Bergh; Snezana Andrejevic-Blant; Jean-Francois Savary; Philippe Monnier
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Photodynamic effect on specific antitumor immune activity
Author(s): Veronique Vonarx-Coinsmann; Marie-Therese Foultier; Laurent Morlet; Leonor Xavier de Brito; Thierry Patrice
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Fluorescence spectroscopy for colon cancer diagnosis
Author(s): George I. Zonios; Robert M. Cothren; Joseph Arendt; Jun Wu; James M. Crawford; Jacques Van Dam; Ramasamy Manoharan; Michael S. Feld
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Fluorescence tissue distribution of methylene blue used for photodynamic therapy of Helicobacter Pylori
Author(s): Charles E. Millson; Giovanni A. Buonaccorsi; Alexander J. MacRobert; Peter Mlkvy; Stephen G. Bown
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Photodynamic therapy in early esophageal squamous cell carcinoma
Author(s): Pasquale Spinelli; Marco Dal Fante; Andrea Mancini; Renato Massetti; Emmanuele Meroni
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Effectiveness of photodynamic therapy with a diode laser using mono-L-aspartyl chlorin e6 for implanted fibrosarcoma in mice
Author(s): Tohichiro Katsumi; Katsuo Aizawa; Yukari Kuroiwa; Yoshiteru Ii; Kouichi Saito; X. Ilyar; Tetsuya Okunaka; Chimori Konaka; Harubumi Kato
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Cell death mechanisms vary with photodynamic therapy dose and photosensitizer
Author(s): Jin He; Nancy L. Oleinick
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Intracellular uptake kinetics of hypocrellin photosensitizers for photodynamic therapy
Author(s): Gerald G. Miller; Kevin Brown; Ronald B. Moore; Zhenjun Diwu; Jixiang Liu; Liren Huang; J. William Lown; David A. Begg; Vera Chlumecky; John Tulip; Malcolm S. McPhee
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In vivo monitoring of photosensitizer fluorescence during photodynamic therapy
Author(s): Mark R. Stringer; Dominic J. Robinson; Emma J. Hudson; Michael A. Smith
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Fluorescence imaging photodetection of early cancer in the bronchi with mTHPC and in the bladder with ALA-induced protoporphyrin IX: preliminary clinical results
Author(s): Martin Forrer; Jerome C. Mizeret; Daniel Braichotte; Georges A. Wagnieres; Jean-Francois Savary; Philippe Monnier; Patrice Jichlinski; Hans-Juerg Leisinger; Hubert van den Bergh
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In vivo fluorescence imaging of lysosomes: a potential technique to follow dye accumulation in the context of PDT?
Author(s): Jean-Marie Devoisselle; Serge R. Mordon; Sylvie Soulie-Begu
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Enhanced photodynamic therapy and dosimetry by light-induced fluorescence
Author(s): Daniel Braichotte; Jean-Francois Savary; Philippe Monnier; Hubert van den Bergh
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Clinical and experimental results of photodynamic therapy in neurosurgery
Author(s): Herwig Kostron; B. W. Hochleitner; Alois Obwegeser; M. Seiwald
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Fluorescence diagnostics of head and neck cancer utilizing oral administration of delta-amino levulinic acid
Author(s): Katarina Svanberg; Ingrid Wang-Nordman; R. Rydell; A. Elner; J. Wennerberg; Laudelina C. Pais Clemente; E. Cardosa; R. Pratas; Manuel P. Pais Clemente; Stefan Andersson-Engels; Sune Svanberg
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Response of U-87MG in nude rats in photodynamic therapy
Author(s): Mary O. Dereski; Michael Chopp; Lara Madigan; Norbert Roosen
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Light distribution and optical coefficients in prostate tumor
Author(s): Ase M. Ballangrud; P. J. Wilson; Gerald G. Miller; Ronald B. Moore; Malcolm S. McPhee; John Tulip
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Tumor-localizing fluorescent diagnostic agents without phototoxicity: HAT-D01
Author(s): Takeshi Takemura; Shiro Umeuchi; Susumu Nakajima; Isao Sakata
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Measurement of the photodynamic dose in an optical phantom
Author(s): Emma J. Hudson; Mark R. Stringer; Jack Schofield; John Griffiths; Michael A. Smith
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Photodynamic therapy of malignant mesothelioma of pleura
Author(s): Trond Warloe; Helen Heyerdahl; Qian Peng; J. Hoie; E. Normann; O. Solheim; Johan Moan; Karl-Erik Giercksky
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In vivo and in vitro absorption spectrum of disulphonated aluminum phthalocyanine in tumor-bearing mice
Author(s): Rinaldo Cubeddu; Gianfranco L. Canti; Antonio Pifferi; Paola Taroni; Gianluca Valentini
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Significance of threshold doses for photodynamic therapy of melanotic and amelanotic tumors
Author(s): Joerg G. Moser; R. Suchomski; Till Danielowski; Birgit Wagner; H. Scheer; G. Hartwich
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Tissue distribution of liposomal zinc(II)-phthalocyanine in normolipaemic and hyperlipaemic rats following intravenous administration
Author(s): William G. Love; Patrick C.N. Rensen; Ute Isele; Peter W. Taylor
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Localization of zinc(II)-phthalocyanine within implanted tumors after intravenous administration of a liposomal formulation
Author(s): Saskia Duk; Roberta Biolo; William G. Love; Giulio Jori; Peter W. Taylor
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Photodynamic response of an endothelial hybridoma cell line using zinc(II) tetrasubstituted phthalocyanines
Author(s): Janet E. Cruse-Sawyer; B. Dixon; David J.H. Roberts; John Griffiths; Stanley B. Brown
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Chemical instability of 5-aminolevulinic acid (ALA) in aqueous solution
Author(s): Mercedes Novo Rodriguez; Gereon Huettmann; Heyke Cacile Diddens
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Increased vascular permeability of solid tumors causes selectivity of 5-aminolevulinic acid (ALA) induced porphyrins
Author(s): Christoph Abels; Peter Heil; Marc Dellian; Gerhard E.H. Kuhnle; Reinhold Baumgartner; Alwin E. Goetz
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Exogenous delta-animolevulinic acid induces the porphyrin biosynthesis in human skin organ cultures with different porphyrin patterns in normal and malignant human tissue
Author(s): Clemens Fritsch; Janine Batz; Klaus Bolsen; Klaus Schulte; Thomas Ruzicka; Guenter Goerz
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Topical photodynamic therapy with 5-ALA in the treatment of arsenic-induced skin tumors
Author(s): Sigrid Karrer; Rolf-Markus Szeimies; Michael Landthaler
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Photodynamic therapy with 5-aminoolevulinic acid-induced porphyrins and DMSO/EDTA for basal cell carcinoma
Author(s): Trond Warloe; Qian Peng; Helen Heyerdahl; Johan Moan; Harald B. Steen; Karl-Erik Giercksky
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Photodynamic therapy with aminolevulinic acid and meso-tetrahydroxyphenylchlorin: first initial clinical experience in Egypt
Author(s): Mohamed El Far; A. Setate; M. El-Maadawy
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Photodynamic therapy of nonmelanoma skin malignancies with topical delta-amino levulinic acid: diagnostic measurements
Author(s): Ingrid Wang-Nordman; Katarina Svanberg; Stefan Andersson-Engels; Roger Berg; Sune Svanberg
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Photodynamic therapy using 5-aminolaevulinic acid in oral malignancy and premalignancy
Author(s): Colin Hopper; Kathleen F.M. Fan; William E. Grant; Paul M. Speight; Stephen G. Bown
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Meta-tetrahydroxyphenylchlorin (mTHPC) mediated photodynamic therapy: experience and thoughts after 17 treatments
Author(s): Mike G. Dilkes; Martin L. DeJode
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Detection of singlet oxygen yield from new photosensitizers using luminol
Author(s): Harumasa Sakai; Hugo Oppelaar; Paul Baas; Nico Van Zandwijk; Fiona A. Stewart
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Distribution and photodynamic effect of meta-tetrahydroxyphenylchlorin (mTHPC) in the pancreas and adjacent tissues in Syrian golden hamsters
Author(s): Peter Mlkvy; Helmut Messmann; J. C. Stewart; M. Pauer; Charles E. Millson; Alexander J. MacRobert; Stephen G. Bown
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Model of the haem biosynthetic pathway
Author(s): Jeanette Greaves-Brown; Tim J. Williams; J. H. Parish
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HepG2 human hepatocarcinomas cells sensitization by endogenous porphyrins
Author(s): Veronique Vonarx-Coinsmann; Marie-Therese Foultier; Leonor Xavier de Brito; Laurent Morlet; Thierry Patrice
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Urothelial conversion of 5-aminolevulinic acid to protoporphyrin IX following oral or intravesical administration
Author(s): Ronald B. Moore; Gerald G. Miller; Kevin Brown; Rakesh Bhatnagar; John Tulip; Malcolm S. McPhee
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Biodistribution and photodynamic effect of protoporphyrin IX in rat urinary bladders after intravesical instillation of 5-aminolaevulinic acid
Author(s): Shi-Chung Chang; Alexander J. MacRobert; Stephen G. Bown
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Tumor responses after combined PDT and hyperthermia
Author(s): Fred W. Hetzel; H. Chen; Qun Chen
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Is photodynamic therapy a selective treatment? Analysis of local complications after endoscopic photodynamic therapy of early stage tumors of gastrointestinal, tracheobronchial, and urinary tracts
Author(s): Pasquale Spinelli; Marco Dal Fante; Andrea Mancini
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7, 12 dimethylbenz(a)anthracene(DMBA)-induced "early" Squamous Cell carcinoma in the Golden Syrian hamster: evaluation of an animal model and comparison with "early" forms of human Squamous Cell car
Author(s): Snezana Andrejevic-Blant; Jean-Francois Savary; Charlotte Fontolliet; Philippe Monnier
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Effect of tin etiopurpurin and light on the canine prostate
Author(s): Steven H. Selman; Rick W. Keck; Daniel R. Doiron
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Removal of the intestinal mucosa: photochemical approach in bladder augmentation
Author(s): Gregory D. Haselhuhn; Kenneth A. Kropp; Rick W. Keck; Steven H. Selman
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Application of 1,2-diethyl-3-hydroxypyridin-4-one to enhance tissue selectivity for photodynamic therapy of the bladder
Author(s): Shi-Chung Chang; Alexander J. MacRobert; John B. Porter; Stephen G. Bown
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New cancer-treatment model of photodynamic therapy combined with a type I topoisomerase inhibitor, CPT-11, against HeLa cell tumors in nude mice used by OPO parametric tunable laser
Author(s): Takato O. Yoshida; Eiji Matsuzawa; Tetsumichi Matsuo; Yukio Koide; Susumu Terakawa; Teruo Yokokura; Toru Hirano
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Photodynamic therapy with cationic photosensitizers
Author(s): David Kessel; Kathryn W. Woodburn; Chi Kwong Chang; Barbara W. Henderson
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Serum levels of hematoporphyrin derivatives in the photodynamic therapy of malignant tumors
Author(s): H. K. Chan; K. S. Low; A. S. Haji Baba; S. Arimbalam; C. H. Yip; K. W. Chang; G. Baskaran; Y. L. Lo; P. Jayalakshmi; L. M. Looi; N. H. Tan
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Tumor-associated macrophages (not tumor cells) are the determinants of photosensitizer tumor localization
Author(s): Mladen Korbelik; Gorazd Krosl
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Potentiation of photodynamic therapy by granulocyte-macrophage colony stimulating factor immunotherapy
Author(s): Gorazd Krosl; Mladen Korbelik; Jana Krosl; Graeme J. Dougherty
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Mechanism of photodynamic therapy (PDT): investigation of sensitizer dose and light dose-rate effects
Author(s): Takeshi Takemura; Shiro Umeuchi; Susumu Nakajima; Isao Sakata
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Tissue discrimination by means of stochastic analysis of backscattered light
Author(s): Rudolf H. Jindra
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New light source for PDT of skin lesions
Author(s): Rolf-Markus Szeimies; Sigrid Karrer; Alfred Heine; Wolfgang Baeumler; Michael Landthaler
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Assessment of noncoherent light sources for photodynamic therapy
Author(s): Roy H. Pottier; Eva F. Gudgin Dickson; Pierre Nadeau; Helmut Wieland; Kasimir Sosin; James C. Kennedy
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Sensitization and photodynamic therapy of esophageal, duodenal, and colonic tumors with 5-aminolaevulinic acid (ALA) induced protoporphyrinIX (PPIX)
Author(s): Peter Mlkvy; Helmut Messmann; Jaroslaw Regula; M. Conio; M. Pauer; Charles E. Millson; Alexander J. MacRobert; Stephen G. Bown
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Barrett's esophagus: photodynamic therapy for ablation of dysplasia, reduction of specialized mucosa and treatment of superficial esophageal cancer
Author(s): Bergein F. Overholt; Masoud Panjehpour
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Preliminary report of clinical application of hematoporphyrin monomethyl ether in photodynamic therapy for alimentary cancers
Author(s): Ying Gu; Junheng Li; De-Yu Xu; Zi-Qi Zhang; Yingcai Huang; Kai Wang
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Clinical measurements of tissue optical properties in the esophagus and in the oral cavity
Author(s): Roland Bays; Georges A. Wagnieres; D. Robert; Jerome C. Mizeret; Daniel Braichotte; Jean-Francois Savary; Philippe Monnier; Hubert van den Bergh
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5-aminolaevulinic acid for fluorescence diagnosis and photodynamic therapy of bronchial cancer: a case report
Author(s): Fernando Gamarra; Reinhold Baumgartner; Herbert G. Stepp; Kai Rick; A. Leberig; Rudolf M. Huber
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Photodynamic therapy--1994: treatment of benign and malignant upper aerodigestive tract disease
Author(s): Vanessa Gayl Schweitzer
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Determination of threshold dose with delta-aminolevulinic acid-induced porphyrins for effective photodynamic therapy
Author(s): Clemens Fritsch; Christoph Abels; Klaus Bolsen; Thomas Ruzicka; Alwin E. Goetz; Guenter Goerz
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Photodynamic therapy of normal canine prostate
Author(s): Qun Chen; Sugandh D. Shetty; Brian C. Wilson; Michael S. Patterson; Larry Heads; Daniel Schultz; Joseph C. Cerny; H. Chen; Fred W. Hetzel
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Usefulness of a wavelength tunable optical parametric oscillator laser on photodynamic therapy
Author(s): Yoshiro Nishiwaki; Takato O. Yoshida; Satoshi Nakamura; Shozo Baba; Eiji Matsusawa; Hideo Suzuki; Toru Hirano
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Information computer program for laser therapy and laser puncture
Author(s): Nadegda N. Badovets; Andrei V. Medvedev
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In vivo comparison of 630-nm laser and broad spectrum nonlaser light for topical 5-animolaevulinic acid photodynamic therapy
Author(s): G. I. Stables; Mark R. Stringer; B. Dixon; Stanley B. Brown
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Photodynamic therapy (PDT) for locally recurrent breast carcinoma
Author(s): Johannes Gahlen; Josef Stern; Georgi Graschew; Michael R. Kaus; Christian Herfarth
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Photodynamic therapy on normal rabbit mandible
Author(s): Kathleen F.M. Fan; Colin Hopper; Paul M. Speight; Claire Davies; Stephen G. Bown
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Transcutaneous photodynamic therapy delays the onset of paralysis in a murine multiple sclerosis model
Author(s): David W. C. Hunt; Simon Leong; Julia G. Levy; Agnes H. Chan
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Photodynamic therapy induced leukocyte adherence in normal subcutaneous, but not in tumor microvessels
Author(s): Marc Dellian; Christoph Abels; Gerhard E.H. Kuhnle; Alwin E. Goetz
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Effects of photodynamic treatment on contraction of collagen gels by cultured human dermal fibroblasts
Author(s): Rolf-Markus Szeimies; Anja Katrin Bosserhoff; Ruediger Hein; Armin Dylla; Wolfgang Baeumler; Michael Landthaler
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Photodynamic therapy of arteries: preservation of mechanical integrity
Author(s): William E. Grant; Colin Hopper; Giovanni A. Buonaccorsi; Paul M. Speight; Alexander J. MacRobert; Kathleen F.M. Fan; Stephen G. Bown
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Simple red light sources for photodynamic therapy of malignant tumors
Author(s): K. S. Low; H. K. Chan; A. S. Haji Baba; C. H. Yip; K. W. Chang; Y. L. Lo; P. Jayalakshmi; L. M. Looi
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General-purpose instrument for PDT dosimetry
Author(s): Michael S. Patterson; Joseph E. Hayward; Thomas J. Farrell; Brian C. Wilson
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Performance of a nonlaser light source for photodynamic therapy
Author(s): Colin Whitehurst; Karen T. Byrne; Colin Morton; James V. Moore
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Distribution of protoporphyrin IX in Bowen's disease and basal cell carcinomas treated with topical 5-aminolaevulinic acid
Author(s): David J.H. Roberts; G. I. Stables; D. V. Ash; Stanley B. Brown
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Acoustic, fluorescent diagnosis of malignant lesions using HAT-D01 and ATX-S10
Author(s): Susumu Nakajima; Takeshi Takemura; Isao Sakata
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Meso-tetrahydroxyphenylchlorin (mTHPC) fluorescence kinetics in mice
Author(s): Laurent Morlet; Veronique Vonarx-Coinsmann; Marie-Therese Foultier; Thierry Patrice
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Endoscopic fluorescence of gastrointestinal neoplasia after sensitization with 5-aminolaevulinic acid (ALA) or Photofrin
Author(s): Helmut Messmann; Peter Mlkvy; Sune Montan; Ingrid Wang-Nordman; Annika M.K. Nilsson; Katarina Svanberg; Sune Svanberg; Alexander J. MacRobert; Stephen G. Bown
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Fluorescence detection of premalignant, malignant, and micrometastatic disease using hexylpyropheophorbide
Author(s): Kinya Furukawa; David H. Crean; Thomas S. Mang; Harubumi Kato; Thomas J. Dougherty
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Measurements of sensitizer fluorescence in patients by means of an ordinary fluorescence spectrometer
Author(s): Johan Moan; Elfrid Hoydalsvik; Qian Peng; Li Wei Ma; Trond Warloe; Helen Heyerdahl
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Photodynamic therapy for early gastric cancer: its application for wider lesions
Author(s): Seishiro Mimura; Hiroyuki Narahara; Toru Otani; Shigeru Okuda
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Usefulness of threshold dose to prevent damage of underlying tissue by PDT treatment: an in-vitro study on chondrocytes
Author(s): R. Placzek; G. Kempka; W. Ruether; Joerg G. Moser
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Hydrokolloid occlusive dressings for photodynamic therapy (PDT) of cutaneous lesions with endogenous porphyrins induced by 5-aminolevulinic acid
Author(s): Johannes Gahlen; Josef Stern; Christian Herfarth
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Photodynamic therapy (PDT) for perianal bowenoid papulosis
Author(s): Johannes Gahlen; Josef Stern; Georgi Graschew; Michael R. Kaus; W. Tilgen
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Threshold effects of PDT in the normal rat colon with ALA photosensitization
Author(s): Helmut Messmann; Peter Mlkvy; Claire Davies; Alexander J. MacRobert; Stephen G. Bown
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Tunable laser-based illumination system for cells in monolayer
Author(s): Janet E. Cruse-Sawyer; Mark R. Stringer
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Syntheses, photophysical and first aspects of the photosensitizing properties of a new water-soluble SiPc
Author(s): Silke Mueller; Dieter Woehrle; Maria Shopova; Beate Roeder; Maria Schoenermark
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Absorption spectroscopic analysis of the pharmacokinetics of octa-alpha-butyloxy-zinc phthalocyanine in Lewis lung carcinoma-bearing mice
Author(s): Cathrin Dressler; M. Samy Ismail; Simone Stroebele; Christian Nowak; Ralf Herter; Rainier G. Senz; Roland Hagemann; Peter Koeppe; Beate Roeder; Hans-Peter Berlien
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Percutaneous transluminal photodynamic therapy of atheroma using mono-L-aspartyl chlorin e6
Author(s): Junichi Hayashi; Hideaki Sato; Takashi Saito; Yukari Kuroiwa; Katsuo Aizawa; Tatsushi Fujiwara; Yasuhiro Hosoda
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Photodynamic therapy of the atherosclerotic abdominal aorta by laparoscopical approach using a pheophorbide derivative
Author(s): Takashi Saito; Junichi Hayashi; Hideaki Sato; Hirofumi Kawabe; Katsuo Aizawa
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New diffuser/applicator for use in the treatment of esophageal cancer by photodynamic therapy
Author(s): Emma J. Hudson; Mark R. Stringer; Kate Dixon; Keyvan Moghissi
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Phototransformation of ALA-induced protoporphyrin IX (PPIX) in carcinoma cells and of exogenous PPIX in cells and solutions
Author(s): W. Dietel; Ronald Wendenburg
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PDT-induced apoptosis in arterial smooth muscles cells
Author(s): Isaac Nyamekye; R. Renick; C. Gilbert; Jean R. McEwan; G. Evan; Christopher C. R. Bishop; Stephen G. Bown
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Brain response to photodynamic therapy and Photofrin, nonsulfonated aluminum phthalocyanine and tin purpurin
Author(s): Mary O. Dereski; Lara Madigan; Michael Chopp
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Wavelength-dependent photodynamic inactivation of HaCaT human keratinocytes after preincubation with 5-aminolevulinic acid
Author(s): Rolf-Markus Szeimies; Wolfgang Baeumler; Sigrid Karrer; Michael Landthaler
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New approach for treatment of advanced malignant tumors: combination of chemotherapy and photodynamic therapy
Author(s): Lian-xing Wang; Hua-lamg Ju; Zhem-ming Chem
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Treatment of rheumatoid arthritis using photodynamic therapy
Author(s): Christian Hendrich; Heyke Cacile Diddens; Hany R. Nosir; Werner E. Siebert
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Treatment of experimental murine arthritis with transdermal photodynamic therapy
Author(s): Leslie G. Ratkay; R. K. Chowdhary; Herma C. Neyndorff; Julia G. Levy; J. D. Waterfield
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Improved method of laser photovaporization for endometrium cases
Author(s): En-ju Xia; Hua Lu; En-ling Chen; Hong-yue Wan
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Detection of active oxygen species in a photosensitizing reaction in vitro by ESR measurements
Author(s): Norio Miyoshi
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Tissue Fluorescence
Author(s): Steven L. Jacques
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