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Proceedings Paper

Blood Flow Changes In Transplantable Urothelial Tumors Treated With The Metallopurpurin, SnET2 And Light.
Author(s): Steven H. Selman; Binsheng Qin; Harold R. James; Rick W. Keck; Greta M. Garbo; Alan R. Morgan
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Paper Abstract

Changes in blood flow to transplantable bladder tumors growing in Fischer rats were measured after photodynamic therapy with the photosensitizer tin (II) etiopurpurin dichloride (SnET2) using the radioactive microsphere technique. As with the other photosensitizers, hematoporphyrin derivative and chloroaluminum tetrasulfophthalocyanine, SnET2 and light caused a rapid decrease in tumor blood flow. This occurred when the vehicle for photosensitizer delivery was either an emulsion or a liposome. Systemic heparinization of animals did not alter changes in tumor blood flow.

Paper Details

Date Published: 13 June 1989
PDF: 7 pages
Proc. SPIE 1065, Photodynamic Therapy: Mechanisms, (13 June 1989); doi: 10.1117/12.978001
Show Author Affiliations
Steven H. Selman, University of Toledo (United States)
Binsheng Qin, University of Toledo (United States)
Harold R. James, University of Toledo (United States)
Rick W. Keck, University of Toledo (United States)
Greta M. Garbo, University of Toledo (United States)
Alan R. Morgan, University of Toledo (United States)

Published in SPIE Proceedings Vol. 1065:
Photodynamic Therapy: Mechanisms
Thomas J. Dougherty, Editor(s)

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