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Proceedings Paper

Label-free DNA biosensor based on cladding-etched thin-core fiber modal interferometer
Author(s): Guiying Ma; A. Ping Zhang; Guofeng Yan; Yinbing Bai; Yichuan Hu; Xuesong Ye
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Paper Abstract

The fabrication and characterization of a highly sensitive DNA biosensor based on thin-core fiber modal interferometer (TCFMI) are presented. The TCFMI is made by using a thin-core fiber (TCF) with core diameter of ~3.0 μm and etched by using Hydrofluoric (HF) acid solution for sensitivity enhancement. A thin layer of polymer (PLL, poly-L-lysine) was coated on the sensor surface and experimentally demonstrated for the detection of hybridization of deoxyribonucleic acid (DNA).

Paper Details

Date Published: 7 November 2012
PDF: 4 pages
Proc. SPIE 8421, OFS2012 22nd International Conference on Optical Fiber Sensors, 84215Q (7 November 2012); doi: 10.1117/12.974989
Show Author Affiliations
Guiying Ma, Zhejiang Univ. (China)
Joint Research Lab. of Optics of Zhejiang Normal Univ. and Zhejiang Univ. (China)
A. Ping Zhang, Zhejiang Univ. (China)
Joint Research Lab. of Optics of Zhejiang Normal Univ. and Zhejiang Univ. (China)
Guofeng Yan, Zhejiang Univ. (China)
Joint Research Lab. of Optics of Zhejiang Normal Univ. and Zhejiang Univ. (China)
Yinbing Bai, Zhejiang Univ. (China)
Joint Research Lab. of Optics of Zhejiang Normal Univ. and Zhejiang Univ. (China)
Yichuan Hu, Zhejiang Univ. (China)
Zhejiang Univ. of Technology (China)
Xuesong Ye, Zhejiang Univ. (China)


Published in SPIE Proceedings Vol. 8421:
OFS2012 22nd International Conference on Optical Fiber Sensors
Yanbiao Liao; Wei Jin; David D. Sampson; Ryozo Yamauchi; Youngjoo Chung; Kentaro Nakamura; Yunjiang Rao, Editor(s)

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