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Proceedings Paper

An IR Spectroscopic Characterization Of The Blood Component Platelet Activating Factor
Author(s): E. C. Mushayakarara; H. H. Mantsch
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Paper Abstract

The platelet activating factor, PAF, has been recently identified as an ether lipid with dramatic bioreactivity. The present IR spectroscopic investigation demonstrates that in an aqueous environment PAF can assume three different structures, a micellar form at tempera-tures above 21°C, a solid-like opaque lamellar form at temperatures below 12°C, and an intermediate transparent lamellar form that exists at temperatures between 12 and 21°C. The three structures are separated by two reversible phase transitions; however, the rate of the reversed micellar to lamellar change is negatively temperature dependent, i.e., about 6 min at -1°C and 12 min at 3°C, and slower than the lamellar to micellar change.

Paper Details

Date Published: 20 December 1985
PDF: 2 pages
Proc. SPIE 0553, Fourier and Computerized Infrared Spectroscopy, (20 December 1985); doi: 10.1117/12.970751
Show Author Affiliations
E. C. Mushayakarara, National Research Council of Canada (Canada)
H. H. Mantsch, National Research Council of Canada (Canada)


Published in SPIE Proceedings Vol. 0553:
Fourier and Computerized Infrared Spectroscopy
David G. Cameron; Jeannette G. Grasselli, Editor(s)

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