Share Email Print
cover

Proceedings Paper

Optical sensing: recognition elements and devices
Author(s): Guenter G. Gauglitz
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

The requirements in chemical and biochemical sensing with respect to recognition elements, avoiding non-specific interactions, and high loading of the surface for detection of low concentrations as well as optimized detection systems are discussed. Among the many detection principles the optical techniques are classified. Methods using labeled compounds like Total Internal Reflection Fluorescence (TIRF) and direct optical methods like micro reflectometry or refractometry are discussed in comparison. Reflectometric Interference Spectroscopy (RIfS) is presented as a robust simple method for biosensing. As applications, trace analysis of endocrine disruptors in water, hormones in food, detection of viruses and bacteria in food and clinical diagnostics are discussed.

Paper Details

Date Published: 19 November 2012
PDF: 10 pages
Proc. SPIE 8545, Optical Materials and Biomaterials in Security and Defence Systems Technology IX, 85450F (19 November 2012); doi: 10.1117/12.970550
Show Author Affiliations
Guenter G. Gauglitz, Eberhard Karls Univ. Tübingen (Germany)


Published in SPIE Proceedings Vol. 8545:
Optical Materials and Biomaterials in Security and Defence Systems Technology IX
Roberto Zamboni; François Kajzar; Attila A. Szep, Editor(s)

© SPIE. Terms of Use
Back to Top