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Proceedings Paper

A Digital Optically Multiplexed Charge Coupled Device (CCD) Based Deoxyribonucleic Acid (DNA) Sequence Reader
Author(s): Eric R. Craine; Brian L. Craine; John R. Engel; Neil T. Wemple; Ron Hilliard
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Paper Abstract

We have developed a unique prototype solid state digital imaging system for use in the analysis of one dimensional deoxyribonucleic acid (DNA) sequencing gels. The system can be used to digitize, interpret and store DNA sequence information directly from an autoradiogram. The system consists of a two dimensional charge coupled device (CCD) imager, a multiplexing optical front end for reformatting of the gel image, a microcomputer host and a software package for reconstruction of the gel image and analysis of the DNA sequence.

Paper Details

Date Published: 27 June 1988
PDF: 6 pages
Proc. SPIE 0914, Medical Imaging II, (27 June 1988); doi: 10.1117/12.968675
Show Author Affiliations
Eric R. Craine, Western Research Company, Inc. (United States)
Brian L. Craine, Western Research Company, Inc. (United States)
John R. Engel, Western Research Company, Inc. (United States)
Neil T. Wemple, Western Research Company, Inc. (United States)
Ron Hilliard, Optomechanics Research, Inc. (United States)


Published in SPIE Proceedings Vol. 0914:
Medical Imaging II
Samuel J. Dwyer; Roger H. Schneider; Roger H. Schneider; Samuel J. Dwyer; Samuel J. Dwyer; Roger H. Schneider, Editor(s)

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