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Proceedings Paper

NIKOS II - A System For Non-Invasive Imaging Of Coronary Arteries
Author(s): W.-R. Dix; K. Engelke; G. Heintze; J. Heuer; W. Graeff; W. Kupper; M. Lohmann; I. Makin; T. Mochel; R. Reumann
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Paper Abstract

This paper presents results of the initial in-vivo investigations with the system NIKOS II (NIKOS = Nicht-invasive Koronarangiographie mit Synchrotronstrahlung), an advanced version of NIKOS I which was developed since 1981. Aim of the work is to be able to visualize coronary arteries down to 1mm diameter with an iodine mass density of lmg/cm2, thus allowing non-invasive investigations by intravenous injection of the contrast agent. For this purpose Digital Subtraction Angiography (DSA) in energy subtraction mode (dichromography) is employed. The two images for subtraction are taken at photon energies just below and above the iodine K-edge (33.17keV) After subtraction the background contrast from bone and soft tissue is suppressed and the iodinated structures are strongly enhanced because of the abrupt change of absorption at the K-edge. The two monoenergetic beams are filtered out of a synchrotron radiation beam by a crystal monochromator and measured with a two line detector. One scan (two images) lasts between 250ms (final version) and ls (at present ). The images from the in-vivo investigations of dogs have been promising. The right coronary artery (diameter 1.5mm) was clearly visible. With application of better image processing algorithms the images illustrated in this paper have a definite potential for improvement.

Paper Details

Date Published: 1 May 1989
PDF: 14 pages
Proc. SPIE 1090, Medical Imaging III: Image Formation, (1 May 1989); doi: 10.1117/12.953213
Show Author Affiliations
W.-R. Dix, Hamburger Synchrotronstrahlungslabor HASY LAB (Germany)
K. Engelke, Hamburger Synchrotronstrahlungslabor HASY LAB (Germany)
G. Heintze, Hamburger Synchrotronstrahlungslabor HASY LAB (Germany)
J. Heuer, Hamburger Synchrotronstrahlungslabor HASY LAB (Germany)
W. Graeff, Hamburger Synchrotronstrahlungslabor HASY LAB (Germany)
W. Kupper, Universitats-Krankenhaus Eppendorf (Germany)
M. Lohmann, Universitats-Krankenhaus Eppendorf (Germany)
I. Makin, Fachhochschule Hamburg (Germany)
T. Mochel, Universitat Hamburg (Germany)
R. Reumann, Universitat Hamburg (Germany)

Published in SPIE Proceedings Vol. 1090:
Medical Imaging III: Image Formation
Samuel J. Dwyer; R. Gilbert Jost; Roger H. Schneider, Editor(s)

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