Share Email Print

Proceedings Paper

Intracoronary Doppler: Clinical Application And Future Directions
Author(s): Patrick L. Whitlow; Russell E. Raymond; E. Murat Tuzcu
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

Because coronary arteriography may underestimate the severity of coronary artery disease, other methods to assess the physiologic significance of a coronary lesion have been sought. Experimental data have confirmed that the ratio of peak flow to resting flow, coronary vasodilator reserve (CVDR), is a quantitative measure of the functional significance of a coronary a stenosis. A 20 MHz pulsed Doppler catheter with a 1 mm outer diameter and an innerlumen for guidewire placement was developed in 1985 and has been used for clinical measurement of CVDR. The technique appears safe, and reliable signals can be obtained in the vast majority of patients studied. Limitations of the technique include possible changes in vessel diameter with delivery of a vasodilator stimulus, possible elevation of baseline flow above normal resting values which would diminish the CVDR, and inability to measure absolute coronary flow. These limitations could be overcome by the development of an intravascular Echo-Doppler device in the future.

Paper Details

Date Published: 8 August 1989
PDF: 10 pages
Proc. SPIE 1068, Catheter-Based Sensing and Imaging Technology, (8 August 1989); doi: 10.1117/12.952167
Show Author Affiliations
Patrick L. Whitlow, Cleveland Clinic Foundation (United States)
Russell E. Raymond, Cleveland Clinic Foundation (United States)
E. Murat Tuzcu, Cleveland Clinic Foundation (United States)

Published in SPIE Proceedings Vol. 1068:
Catheter-Based Sensing and Imaging Technology
Alan I. West, Editor(s)

© SPIE. Terms of Use
Back to Top