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Proceedings Paper

Photodynamic-Therapy By TPPS Topical Application And Dye-Laser In Basal Cell Carcinoma
Author(s): V. Sacchini; E. Melloni; O. Santoro; R. Marchesini; N. Cascinelli; G. Banctieramonte
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Paper Abstract

Since February 1987 to March 1988, 118 biopsy proven basal cell carcinoma were treated in 22 patients at the National Cancer Institute in Milan. The treatment consisted in the tumor photosensitization by topical administration of Tetraphenyl-porfinesulphonate (TPPS) onto the tumor surface, and red light exposure. The irradiation was performed by an Argon-pumped dye laser at 650 nm. The persistence of the lesions was noted in 4% of the cases. 13% of the cases recurred after 4 months. 35% of these recurrences were at the periphery of the irradiated area, and a second, treatment gave complete tumor regression. Important complications did not occurred; only in 3 cases a moderate skin distrophy resulted.

Paper Details

Date Published: 11 September 1989
PDF: 4 pages
Proc. SPIE 1066, Laser Surgery: Advanced Characterization, Therapeutics, and Systems, (11 September 1989); doi: 10.1117/12.952048
Show Author Affiliations
V. Sacchini, Istituto Nazionale Tumori (Italy)
E. Melloni, Istituto Nazionale Tumori (Italy)
O. Santoro, Istituto Nazionale Tumori (Italy)
R. Marchesini, Istituto Nazionale Tumori (Italy)
N. Cascinelli, Istituto Nazionale Tumori (Italy)
G. Banctieramonte, Istituto Nazionale Tumori (Italy)


Published in SPIE Proceedings Vol. 1066:
Laser Surgery: Advanced Characterization, Therapeutics, and Systems
Kazuhiko Atsumi; Norman R. Goldblatt; Stephen N. Joffe, Editor(s)

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