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Proceedings Paper

Excimer Laser Angioplasty: Initial Clinical Results With A Percutaneous Transluminal Procedure In Total Peripheral Artery Occlusion
Author(s): Gregor Wollenek; Gunther Laufer; Kristian Hohla; Florian Grabenwoger; Walter Klepetko
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Paper Abstract

Laser energy has the potential to recanalize obstructive atherosclerotic vessels as an alternative or an adjunct to either bypass surgery or balloon angioplasty. But conventional lasers cause thermal side effects which may lead to extensive damage to neighboring layers. In contrast, excimer laser irradiation in the far ultraviolet range has proved to minimize or avoid these injuries to vessel walls. To evaluate the clinical feasibility of excimer laser angioplasty (ELA), we have performed basic investigations including histologic examination by light microscopy, scanning and electron microscopy, and temperature measurements, and later on in vivo animal trials. Using 308 nm irradiation (XeCl) we have treated the first patient ever to undergo ELA, and the procedure was successful: after recanalization of a total occlusion of a superficial femoral artery, dilatation resulted in sufficient blood supply to the periphery.

Paper Details

Date Published: 26 April 1989
PDF: 5 pages
Proc. SPIE 1023, Excimer Lasers and Applications, (26 April 1989); doi: 10.1117/12.950160
Show Author Affiliations
Gregor Wollenek, University of Vienna (Austria)
Gunther Laufer, University of Vienna (Austria)
Kristian Hohla, Technolas Lasertechnik GmbH Research Laboratory (F.R.G.)
Florian Grabenwoger, University of Vienna (Austria)
Walter Klepetko, University of Vienna (Austria)

Published in SPIE Proceedings Vol. 1023:
Excimer Lasers and Applications
Dirk Basting, Editor(s)

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