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Proceedings Paper

Organic nanoparticles as a central plateform of magnetofluorescent nano-assemblies toward two-photon bioimaging applications
Author(s): Adrien Faucon; Romarik Lenk; Julie Hemez; Eric Gautron; Jérôme Fresnais; Jean-François Berret; Eléna Ishow
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Paper Abstract

The combined association of magnetic and luminescent properties into a unique object (especially nanoparticle) has recently driven considerable interest since it offers non-invasive dual imaging and permits contactless addressing and vectorization. We report on the use of organic materials, known to emit in the solid state and form size-controlled nanoparticles upon precipitation. They generate cohesive magnetofluorescent hybrid nanospheres without requiring prior coating of the inorganic entities. Their internalization in living cells is successfully proved by two-photon laser scanning fluorescence microscopy and TEM imaging. Deeper photophysical analyses reveal two kinds of structure depending on the solvent and concentration conditions.

Paper Details

Date Published: 10 October 2012
PDF: 9 pages
Proc. SPIE 8464, Nanobiosystems: Processing, Characterization, and Applications V, 84640N (10 October 2012); doi: 10.1117/12.946364
Show Author Affiliations
Adrien Faucon, CEISAM, CNRS, Univ. de Nantes (France)
Romarik Lenk, CEISAM, CNRS, Univ. de Nantes (France)
Julie Hemez, CEISAM, CNRS, Univ. de Nantes (France)
Eric Gautron, IMN, CNRS, Univ. de Nantes (France)
Jérôme Fresnais, PECSA, CNRS, Univ. Paris 6 (France)
Jean-François Berret, MSC, CNRS, Univ. Paris 7 Diderot (France)
Eléna Ishow, CEISAM, CNRS, Univ. de Nantes (France)

Published in SPIE Proceedings Vol. 8464:
Nanobiosystems: Processing, Characterization, and Applications V
Norihisa Kobayashi; Fahima Ouchen; Ileana Rau, Editor(s)

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