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Proceedings Paper

Immunofluorescence Detection For Fiber Optics Chemical And Biological Sensors
Author(s): T Vo -Dinh; B J Tromberg; M J Sepaniak; G D Griffin; K R Ambrose; R M Santella
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Paper Abstract

This paper presents the development and applidation of immunofluorescence spectroscopy in fiberoptics-based chemical and biological sensors. Focus is on a fluoroimmuno-sensor (FIS), which combines the excellent specificity of the antigen-antibody reaction and the high sensitivity of laser excitation and the versatility of fiberoptics technology. The FIS can detect 40 attomoles (10-18 mole) of benzo(a)pyrene tetrol, a DNA-adduct product of the carcinogen benzo(a)pyrene.

Paper Details

Date Published: 27 April 1988
PDF: 8 pages
Proc. SPIE 0910, Fluorescence Detection II, (27 April 1988); doi: 10.1117/12.945444
Show Author Affiliations
T Vo -Dinh, Oak Ridge National Laboratory (United States)
B J Tromberg, University of Tennessee (United States)
M J Sepaniak, University of Tennessee (United States)
G D Griffin, Oak Ridge National Laboratory (United States)
K R Ambrose, Oak Ridge National Laboratory (United States)
R M Santella, Columbia University (United States)


Published in SPIE Proceedings Vol. 0910:
Fluorescence Detection II
E. Roland Menzel, Editor(s)

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