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Proceedings Paper

Digital Imaging Fluorescence Microscopy Reveals Intracellular Calcium Ions In Living Cardiac And Smooth Muscle Cells.
Author(s): W Gil Wier; William F Goldman
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Paper Abstract

We have used digital video microscopy to study the relationship of intracellular calcium ion concentration ([Ca2+]i) to the function of living cardiac and vascular smooth muscle cells. The technical goal of our work is to obtain, with high spatial and temporal resolution, "maps" of [Ca2+]i inside single living cells. To relate [Ca2+]i to cell function, such "maps" can be used in conjunction with measurements of cell electrical activity, contractile activity or biochemical assays.

Paper Details

Date Published: 24 June 1988
PDF: 6 pages
Proc. SPIE 0909, Time-Resolved Laser Spectroscopy in Biochemistry, (24 June 1988); doi: 10.1117/12.945410
Show Author Affiliations
W Gil Wier, University of Maryland at Baltimore (United States)
William F Goldman, University of Maryland at Baltimore (United States)

Published in SPIE Proceedings Vol. 0909:
Time-Resolved Laser Spectroscopy in Biochemistry
Joseph R. Lakowicz, Editor(s)

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