Share Email Print
cover

Proceedings Paper

Constrained Tryptophan Has A Monoexponential Decay
Author(s): Melissa C Sattler; William R Cherry; Mary D Barkley
Format Member Price Non-Member Price
PDF $14.40 $18.00
cover GOOD NEWS! Your organization subscribes to the SPIE Digital Library. You may be able to download this paper for free. Check Access

Paper Abstract

The fluorescence decay of tryptophan is complex. Various models have been proposed to account for the multiexponential decay, including ground-state rotamers, excited-state proton transfer, and lifetime distributions.1-4 In order to test the rotamer model, we are studying a series of tryptophan derivatives in which rotation about the Ca-CB and CB-Cy, bonds is constrained. The ground-state conformations are determined by X-ray diffraction, molecular and 1H NMR. Or preliminary results for a tryptophan derivative with the a-amino group incorporated in a six-member ring are described below.

Paper Details

Date Published: 24 June 1988
PDF: 2 pages
Proc. SPIE 0909, Time-Resolved Laser Spectroscopy in Biochemistry, (24 June 1988); doi: 10.1117/12.945389
Show Author Affiliations
Melissa C Sattler, Louisiana State University (United States)
William R Cherry, Louisiana State University (United States)
Mary D Barkley, Louisiana State University (United States)


Published in SPIE Proceedings Vol. 0909:
Time-Resolved Laser Spectroscopy in Biochemistry
Joseph R. Lakowicz, Editor(s)

© SPIE. Terms of Use
Back to Top