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Proceedings Paper

Argon Ion Laser Induced Tissue Fluorescence: Clinical Spectroscopic Studies
Author(s): R. Cothren; T. Kolubayev; B. T. Kjellstrom; R. Richards-Kortum; B. Healy; N. Ratliff; G. Engelmann; F. Loop; J. R. Kramer; C. Kittrell
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Paper Abstract

In conjunction with our project in laser angiosurgery, our group has demonstrated that laser-induced auto-fluorescence can be a reliable means of distinguishing normal artery from atherosclerotic plaque. Recently a number of groups have become interested in this technique as a means of directing ablation of arterial obstructions in vivo. However, until now, diagnostic spectroscopy has been conducted almost solely on excised cadaveric tissues. As a result, questions still remain about 1) the validity of correlating cadaveric tissue fluorescence spectra with those collected in vivo, and 2) the ability to collect reliable florescence spectra from a subject as dynamic as a living patient.

Paper Details

Date Published: 21 June 1988
PDF: 1 pages
Proc. SPIE 0906, Optical Fibers in Medicine III, (21 June 1988); doi: 10.1117/12.945300
Show Author Affiliations
R. Cothren, Cleveland Clinic Foundation (United States)
T. Kolubayev, Massachusetts Institute of Technology (United States)
B. T. Kjellstrom, Cleveland Clinic Foundation (United States)
R. Richards-Kortum, Massachusetts Institute of Technology (United States)
B. Healy, Cleveland Clinic Foundation (United States)
N. Ratliff, Cleveland Clinic Foundation (United States)
G. Engelmann, Cleveland Clinic Foundation (United States)
F. Loop, Cleveland Clinic Foundation (United States)
J. R. Kramer, Cleveland Clinic Foundation (United States)
C. Kittrell, Massachusetts Institute of Technology (United States)

Published in SPIE Proceedings Vol. 0906:
Optical Fibers in Medicine III
Abraham Katzir, Editor(s)

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