Share Email Print
cover

Proceedings Paper

A Role For Photodynamic Therapy In Autologous Bone Marrow Transplantation
Author(s): Fritz Sieber
Format Member Price Non-Member Price
PDF $14.40 $18.00

Paper Abstract

Simultaneous exposure to the amphipathic fluorescent dye merocyanine 540 (MC 540) and light of a suitable wavelength rapidly kills leukemia, lymphoma, and neuroblastoma cells but spares normal pluripotent hematopoietic stem cells. Tests in several preclinical models and early results of a phase I clinical trial suggest that MC 540-mediated photosensitization may be useful for the extracorporeal purging of autologous remission bone marrow grafts.

Paper Details

Date Published: 19 February 1988
PDF: 6 pages
Proc. SPIE 0847, New Directions in Photodynamic Therapy, (19 February 1988); doi: 10.1117/12.942703
Show Author Affiliations
Fritz Sieber, Medical College of Wisconsin (United States)


Published in SPIE Proceedings Vol. 0847:
New Directions in Photodynamic Therapy
Douglas C. Neckers, Editor(s)

© SPIE. Terms of Use
Back to Top