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Proceedings Paper

Structure And Properties Of Novel Benzo[a]phenoxazinium Photochemotherapeutic Agents
Author(s): James W. Foley; Louis Cincotta; Anthony H. Cincotta
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Paper Abstract

The approach used for the development of some novel benzophenoxazinium photosensitizers is presented. Considerations that have influenced the design of these dyes include structure/function relationships pertaining to such properties as selective tumor staining, fluorescent quantum yields and photosensitized singlet oxygen formation (1O2). General trends in the relative photodynamic behavior exhibited by these new dyes in cell culture are discussed. The results indicate that several of the dyes have significant photosensitizing efficacy.

Paper Details

Date Published: 19 February 1988
PDF: 6 pages
Proc. SPIE 0847, New Directions in Photodynamic Therapy, (19 February 1988); doi: 10.1117/12.942694
Show Author Affiliations
James W. Foley, The Rowland Institute for Science (United States)
Louis Cincotta, The Rowland Institute for Science (United States)
Anthony H. Cincotta, Louisiana State University (United States)

Published in SPIE Proceedings Vol. 0847:
New Directions in Photodynamic Therapy
Douglas C. Neckers, Editor(s)

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